Bionanodesign : Old Forms for New Functions / / Maxim Ryadnov

• Record Nr.: UNINA9910968952803321
• Autore: Ryadnov Maxim
• Pubbl/distr/stampa: London, England : , : The Royal Society of Chemistry, , [2022]; ©2022
• ISBN: 9781788010009; 1788010000; 9781788019316; 1788019318
• Edizione: [Second edition.]
• Descrizione fisica: 1 online resource (214 pages)
• Collana: ISSN Series
• Disciplina: 530
• Soggetti: Nanobiotechnologie; Nanobiotechnology; Recombinant molecules; Structure - Activity - Relationship; Structure-activity relationships (Biochemistry)
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Nota di bibliografia: Includes bibliographical references.
• Nota di contenuto: Cover -- Bionanodesign: Old Forms for New Functions 2nd Edition -- Preface to the First Edition -- Preface to the Second Edition -- Contents -- Chapter 1 - Introductory Notes -- References -- Chapter 2 - DNA as a Self- programming Module for Nanodesigns -- 2.1 Introduction -- 2.2 Chemistry of DNA -- 2.3 DNA Topology Motifs -- 2.3.1 Primary DNA Motifs -- 2.3.2 Secondary DNA Motifs -- 2.3.3 Secondary Motifs Without Sticky- ended Cohesion -- 2.4 DNA Tiles -- 2.5 Programmed DNA Assembly -- 2.5.1 DNA Origami -- 2.5.2 DNA Nanotubes: Intermediate Scaffolds for 2D and 3D Systems -- 2.5.3 Biofunctional 3D DNA Origami -- 2.6 Outlook -- References -- Chapter 3 - Bioinspired Nanodesigns for Molecular Encapsulation -- 3.1 Introduction -- 3.2 Old Forms of Macromolecular Encapsulation Inspire Nanoscale Designs -- 3.2.1 Triskelion Topology as a Template for Cage- like Assemblies -- 3.2.2 Cage- like Encapsulation for Nanomaterial Synthesis -- 3.2.3 Native Protein Shell and Virus Templates -- 3.3 The Challenge of Gene ; Therapy: Towards an Artificial Virus -- 3.3.1 Synthetic Polymer Particles for Gene Encapsulation Via Complexation -- 3.3.2 Cationic Peptides Condensing Genes for Intracellular Delivery -- 3.3.3 Lipid, Glyco and Peptide Amphiphiles for Vesicular Nanodesigns -- 3.4 Regular Geometric Forms for Virus- like Designs -- 3.5 Outlook -- References -- Chapter 4 - Nanoscale Designs for Tissue Regeneration -- 4.1 Introduction -- 4.2 The Extracellular Matrix (ECM) - Its Role and Composition -- 4.2.1 Structural ECM Constituents -- 4.2.2 Fibrillogenesis as the Mechanism of Building the ECM -- 4.2.3 ECM Materials from Biological Sources -- 4.3 Mimicking ECM by Design -- 4.3.1 Polymer Mimetics of the ECM -- 4.3.2 Fibrous Mimetics of the ECM -- 4.3.3 Non- collagenous Assembly Mimetics of the ECM -- 4.3.4 Monomorphic Fibre Mimetics versus Matrix Formation.; 4.3.5 Minimalist Fibrous Gelators for an Artificial ECM -- 4.4 Non- matrix Mimetics of the ECM -- 4.5 Outlook -- References -- Chapter 5 - Concluding Remarks -- Subject Index.
• Sommario/riassunto: This new edition highlights contemporary approaches for designing nanostructures that employ naturally derived self-assembling motifs as synthetic platforms.