1.

Record Nr.

UNINA9910968129103321

Autore

Xie Ping <1963->

Titolo

Tetrahymena and human telomerase enzymes : model and dynamics of processive nucleotide and repeat addition translocations / / Ping Xie

Pubbl/distr/stampa

New York, : Nova Science Publishers, c2012

ISBN

1-61942-029-5

Edizione

[1st ed.]

Descrizione fisica

1 online resource (127 p.)

Collana

Cell biology research progress

Disciplina

572.8/633

Soggetti

Tetrahymena

Telomerase

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Model for processive nucleotide and repeat addition translocations by tetrahymena telomerase -- Model for processive nucleotide and repeat addition translocations by human telomerase -- Equation to describe translocation of reverse transcriptase domain along template -- Interaction between DNA primer and TERT -- Dynamics of primer dissociation -- Dynamics of repeat addition translocation -- Repeat addition processivity -- Some comments -- Summary and outlook.

Sommario/riassunto

This text gives a review of the author's previous work on modelling of the processive nucleotide and repeat addition translocations by recombinant Tetrahymena telomerase and proposes an analogous model for recombinant human telomerase.