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1. |
Record Nr. |
UNINA9910968082403321 |
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Autore |
Chen Thomas C |
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Titolo |
Anastin and malignant gliomas / / editor, Thomas C. Chen ; co-editor, Marc Chamberlain |
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Pubbl/distr/stampa |
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[S.l.], : Bentham e Books, [2011] |
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ISBN |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (219 p.) |
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Collana |
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Controversies in neuro-oncology |
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Altri autori (Persone) |
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ChenThomas C |
ChamberlainMarc C |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and indexes. |
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Nota di contenuto |
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01 Cover Page.pdf; 02 Title Page; 03 eBooks End User License Agreement-Website; 04 table of contents; 05 Foreword; 06 PREFACE-Avastin; 07 Contributors; 08 Part 1 BASIC SCIENCE AND RATIONALE; 09 Ch-1; 10 Part 2; 11 Ch-2 Desjardins-Avastin-recurrent-chen; 12 Ch-3 kreisl-Avastin_and_Mailgnant_Gliomas_-_Is_there_a_role[1]-chen; 13 Ch-4 GutinRT-_bev_review_FI_PG_9-22[1]-chen; 14 Ch-5 norden_controversies_6-19-09[1]-chen; 15 Part 3; 16 Ch-6 Reardon_chapter_8[1].29; 17 Ch-7 Mehta-radiationControversies_in_Neuro-Avastin-final[1]-chen |
18 Ch-8 Gilbert-Bevacizumab_and_Malignant_Glioma_final_version_9-14-09[1]-Gilbert-chen19 Part 4; 20 Ch-9 Schiff-Avastin toxicityFinal-Bevacizumab_Toxicity_in_Glioblastoma_with_DS_edits_090109-for_review_11[1]-chen corrected; 21 Ch-10 Rogers Chapter_-_Avastin_and_AC_-_Chamberlain_11-2-09__3_[2]-Chen; 22 Part 5; 23 Ch-11 Raizer- AvastinFinal__2_[1]-chen; 24 Part 6; 25 Ch-12 POPE_GBM_Avastin_Imaging[1]-chen; 26 Ch-13 Butowski-radiographic responses 2-chen; 27 Ch-14 Imaging Responses of Bevacizuma; 28 Ch-15 HENSON091509cleanref[1]-chen; 29 Part 7; 30 Ch-16 Aghi-_Avastin_v2[1]-Chen |
31 Ch-17 Vogelbaum-Surgical Implications-Avastin_Final[1]-chen32 Part 8; 33 Ch-18 chamberlain-BevNovelApplications_8_6_09[1]-chen; |
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34 Ch-19 Levin-Radiation_necrosis-082509-Final[1]-chen; 35 Ch-20 chamberlain-salvage-chen; 36 Part 9; 37 Ch-21 StuppBev_rec_glioma__final[1]-chen; 38 Ch-22 van den Bent-Avastin in Europe-chen; 39 Ch-23 Avastin_Weller_2009-6-30[1]-chen; 40 Ch-24 Wick European pers-chen; 41 Part 10; 42 Ch-25 Sunitinib_ebook_chapter___B_Neyns[1]-chen; 43 Ch-26 nabors-cilengitide-chen; 44 Ch-27 SorafenibChapter_FINAL[2]-chen; 45 Ch-28 Wen-VEGF-trap_8-14-09_FINAL[1]-chen |
46 Ch-29 Batchelor-Gerstner-Dietrich-Cediranib-09-12-09[1]-chen47 Part 11 Conclusion; 48 Ch-30 Gu Development_of_Bevacizumab[1][1]-chen; 49 Author Index -Avastin; 50 Index-final-chen |
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Sommario/riassunto |
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Neuro-oncology is an embryonic field of cancer research with a number of clinical trials in progress. However, the prognosis on neuro-oncologic patients has remained poor. Moreover, several small scale phase I/II trials performed have proved to be inconclusive because of the limited number of patients involved. As a result, many controversies exist in neuro-oncology drug development for which a forum does not exist. This ebook presents a detailed account on the use of avastin in treating cancer patients. A discussion on clinical experiences and the controversial debate among researchers of ava |
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2. |
Record Nr. |
UNINA9911020429803321 |
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Autore |
Barth Lukas Silvester |
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Titolo |
Data Visualization with Category Theory and Geometry : With a Critical Analysis and Refinement of UMAP / / by Lukas Silvester Barth, Hannaneh Fahimi, Parvaneh Joharinad, Jürgen Jost, Janis Keck |
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Pubbl/distr/stampa |
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Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025 |
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ISBN |
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Edizione |
[1st ed. 2025.] |
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Descrizione fisica |
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1 online resource (XIII, 272 p. 91 illus., 36 illus. in color.) |
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Collana |
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Mathematics of Data, , 2731-4111 ; ; 3 |
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Disciplina |
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Soggetti |
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Dimension reduction (Statistics) |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Chapter 1. Introduction -- Chapter 2. Illustrating UMAP on some simple data sets -- Chapter 3. Metrics and Riemannian manifolds -- Chapter 4. Merging fuzzy simplicial sets and metric spaces: A category theoretical approach -- Chapter 5. UMAP -- Chapter 6. IsUMap: An alternative to the UMAP embedding. |
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Sommario/riassunto |
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This open access book provides a robust exposition of the mathematical foundations of data representation, focusing on two essential pillars of dimensionality reduction methods, namely geometry in general and Riemannian geometry in particular, and category theory. Presenting a list of examples consisting of both geometric objects and empirical datasets, this book provides insights into the different effects of dimensionality reduction techniques on data representation and visualization, with the aim of guiding the reader in understanding the expected results specific to each method in such scenarios. As a showcase, the dimensionality reduction method of “Uniform Manifold Approximation and Projection” (UMAP) has been used in this book, as it is built on theoretical foundations from all the areas we want to highlight here. Thus, this book also aims to systematically present the details of constructing a metric representation of a locally distorted metric space, which is essentially the problem that UMAP is trying to address, from a more general perspective. Explaining how UMAP fits into this broader framework, while critically evaluating the underlying ideas, this book finally introduces an alternative algorithm to UMAP. |
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This algorithm, called IsUMap, retains many of the positive features of UMAP, while improving on some of its drawbacks. |
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