1.

Record Nr.

UNINA9910965645303321

Titolo

Systemic treatment of prostate cancer / / edited by Alan Horwich

Pubbl/distr/stampa

Oxford ; ; New York, : Oxford University Press, 2010

ISBN

0-19-174025-X

0-19-960737-0

1-283-34833-0

9786613348333

0-19-157581-X

Edizione

[1st ed.]

Descrizione fisica

1 online resource (102 p.)

Collana

Oxford oncology library

Altri autori (Persone)

HorwichAlan

Disciplina

616.9946306

Soggetti

Prostate - Cancer - Diagnosis

Prostate - Cancer - Treatment

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Contents; Preface; Symbols and abbreviations; Contributors; 1 Biological principles of hormone therapy; 2 PSA as a marker of progression and response in advanced prostate cancer; 3 Neo-adjuvant and adjuvant hormone therapy for high-risk localized prostate cancer; 4 Systemic treatment of recurrence after local therapies; 5 First-line hormone therapy for metastatic prostate cancer; 6 Second- and third-line hormone therapies; 7 Chemotherapy for metastatic prostate cancer; 8 The role of bisphosphonates in the systemic treatment of prostate cancer; 9 Systemic isotope therapy of bone metastasis

10 Biological targets and new drug development for prostate cancerIndex; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; R; S; T; U; V; W; Z

Sommario/riassunto

Prostate cancer is one of the commonest cancers in men in the western world, and the prevalence is rising currently due to improvements in screening and treatment. Serum PSA represents a useful marker of disease. It has frequently a long natural history, creating the opportunities for multiple sequential therapeutic interventions. For patients with high risk local disease or with metastases, endocrine therapy is central to management. Hormone ablation has long been the mainstay ofendocrine therapy in this group of patients, though anti-



androgens, oestrogens and corticosteroids can also cause r