1.

Record Nr.

UNINA9910964649203321

Titolo

Aromatase inhibitors : types, mode of action and indications / / Jean R. Lamonte, editor

Pubbl/distr/stampa

Hauppauge, N.Y., : Nova Science Publishers, c2009

ISBN

1-61668-665-0

Edizione

[1st ed.]

Descrizione fisica

1 online resource (203 p.)

Collana

Cancer etiology, diagnosis and treatments series

Altri autori (Persone)

LamonteJean R

Disciplina

616.99/449061

Soggetti

Aromatase - Antagonists - Therapeutic use

Estrogen - Antagonists - Therapeutic use

Breast - Cancer - Chemotherapy

Ovaries - Cancer - Chemotherapy

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Anti-estrogen agents : aromatase inhibitors; past, present, and future / Masanori Shimodaira and Tomohiro Nakayama -- Aromatase inhibitors : types, mode of action, and indications / Helena Aguilar and Ander Urruticoechea -- Aromatase inhibitors / Mosammat Rashida Begum, Maruf Siddiqui -- Upfront vs. sequential aromatase inhibitors : an ongoing or settled debate? / Tallal Younis ... [et al.] -- Aromatase expression in the endometrium and its role in the development of uterine pathology / Hugo Maia Jr ... [et al.] -- Aromatase inhibitors for the medical treatment of endometriosis / Kaei Nasu ... [et al.] -- An update of the use of aromatase inhibitors in the management of breast cancer / S. Tang, D.A.L. Morgan, and K.L. Cheung -- Aromatase inhibitors in ovulation induction : myth or reality? / Nikolaos P. Polyzos ... [et al.] -- The use of aromatase inhibitors in ovarian cancer and identification of responsive tumors / S.P. Langdon ... [et al.].

Sommario/riassunto

Aromatase inhibitors (AI) are a class of drugs used in the treatment of breast cancer and ovarian cancer in postmenopausal women. Aromatase is an enzyme that synthesises oestrogen and aromatase inhibitors block the synthesis of oestrogen, which is needed in some cancers to grow.