1.

Record Nr.

UNINA9910963353403321

Autore

Garcia-Segura Luis Miguel

Titolo

Hormones and brain plasticity / / Luis Miguel Garcia-Segura

Pubbl/distr/stampa

Oxford ; ; New York, : Oxford University Press, 2009

ISBN

0-19-029613-5

0-19-971682-X

9786612053658

1-282-05365-5

Edizione

[1st ed.]

Descrizione fisica

1 online resource (xiv, 482 pages) : illustrations (some color), plates

Collana

Oxford series in behavioral neuroendocrinology

Disciplina

612.8

Soggetti

Neuroendocrinology

Neuroplasticity

Hormones - physiology

Neuronal Plasticity - physiology

Brain - physiology

Brain - growth & development

Aging - physiology

Neuronal Plasticity

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references (p. 309-443) and indexes.

Nota di contenuto

Contents; Preface and Acknowledgments; Chapter 1 Hormones and the Mutable Brain; Introduction: Endocrine Glands, Brain Plasticity, Homeostasis, Allostasis, and Homeodynamics; The Nervous System is in a Constant State of Remodeling: Cellular Plasticity and Cellular Replacement; The Classic Concept of Brain Plasticity: Cajal's Heritage; Cellular Replacement: A New Concept; Role of Hormones on Brain Mutability: Plasticity and Metaplasticity; Chapter 2 Brain Plasticity Regulates Hormonal Homeodynamics; Introduction: Brain Plasticity Regulates the Activity of Endocrine Glands

Neuroglial Remodeling Associated with Hormonal Secretion by Hypothalamic Magnocellular NeuronsNeuroglial Remodeling in the Neurohypophysis; Neuroglial Remodeling Associated with Parvocellular Hypothalamic Neurons; Neuroglial Remodeling in the Median Eminence;



Brain Plasticity and the Control of Hormonal Homeodynamics: A Recapitulation; Chapter 3 Hormonal Influences on Brain Plasticity: I. Melatonin, Thyroid Hormones and Corticosteroids; Introduction: A Large Variety of Hormones Regulate Brain Plasticity; Hormones or Paracrine Factors?; Melatonin; Thyroid Hormones

Stress, Corticosteroids, and Brain PlasticityChapter 4 Hormonal Influences on Brain Plasticity: II. Sex Hormones; Introduction: Sex Hormones and Brain Remodeling; The First Evidences; Regulation by Estradiol and Progesterone of Synaptic and Glial Remodeling in the Arcuate Nucleus; Regulation by Estradiol and Progesterone of Synaptic Remodeling in the Ventromedial Hypothalamic Nucleus; Regulation by Estradiol and Progesterone of Synaptic Remodeling in the Hippocampus; Regulation by Estradiol and Progesterone of Glial Remodeling in the Hippocampus

Regulation by Estradiol and Progesterone of Adult NeurogenesisRole of Brain Estradiol Synthesis in the Regulation of Synaptic Plasticity and Neuronal Replacement; Androgens, Synaptic Plasticity, and Cellular Replacement in the Song System of Songbirds; Androgens and Synaptic Plasticity in Motoneurons; Androgens, Synaptic plasticity, and Cellular Replacement in the Mammalian Brain; Chapter 5 Hormonal Influences on Brain Plasticity: III. Peptide Hormones; Introduction: Peptide Hormones as Regulators of Brain Remodeling; Vasopressin and Oxytocin; Corticotropin-Releasing Hormone and Urocortins

ProlactinGonadotropin-Releasing Hormone; Insulin; Growth Hormone/Insulin-Like Growth Factor-I; Insulin-Like Growth Factor-I and Synaptic Plasticity; Insulin-Like Growth Factor-I and Adult Neurogenesis; Interactions of Insulin-Like Growth Factor-I and Estradiol in the Regulation of Brain Plasticity; Erythropoietin; Angiotensin; Feeding Hormones: Leptin, Ghrelin and Glucagon-Like Peptide-1; Hormonal Influences on Brain Plasticity: Recapitulation of the Chapters 3, 4 and 5; Chapter 6 Life Stages, Hormones, and Brain Remodeling: Early Hormonal Influences on Brain Mutability

Introduction: Hormonal Imprinting of the Nervous System

Sommario/riassunto

The nervous system has a remarkable capacity for self-reorganization, and in this first systematic analysis of the interaction between hormones and brain plasticity, Luis Miguel Garcia-Segura proposes that hormones modulate metaplasticity in the brain. He covers a wide variety of hormones, brain regions, and neuroplastic events, and also provides a new theoretical background with which to interpret the interaction of hormones and brain remodeling throughout the entire life of the organism.  Garcia-Segura argues that hormones are indispensable for adequately adapting the endogenous neuroplastic