| |
|
|
|
|
|
|
|
|
1. |
Record Nr. |
UNINA9910437619503321 |
|
|
Autore |
Maximov Philipp Y |
|
|
Titolo |
Tamoxifen : pioneering medicine in breast cancer / / Philipp Y. Maximov, Russell E. McDaniel, V. Craig Jordan |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
|
|
|
|
ISBN |
|
|
|
|
|
|
Edizione |
[1st ed. 2013.] |
|
|
|
|
|
Descrizione fisica |
|
1 online resource (218 p.) |
|
|
|
|
|
|
Collana |
|
Milestones in drug therapy |
|
|
|
|
|
|
Altri autori (Persone) |
|
JordanV. Craig (Virgil Craig) |
McDanielRussell E |
|
|
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
Tamoxifen |
Breast - Cancer - Chemoprevention |
Breast - Cancer - Chemotherapy |
|
|
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
Description based upon print version of record. |
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references. |
|
|
|
|
|
|
Nota di contenuto |
|
Discovery and Pharmacology of Nonsteroidal Estrogens and Antiestrogens -- Tamoxifen Goes Forward Alone -- Metabolites of Tamoxifen as the Basis of Drug Development -- Adjuvant Therapy – The Breakthrough -- The Wisconsin Story in the 1980’s: Discovery of Target Site Specific Estrogen Action -- Carcinogenesis and Tamoxifen -- Chemoprevention: Cinderella waiting for the ball -- Tamoxifen and Raloxifene head to head: The STAR TRIAL -- Acquired resistance to Tamoxifen: back to the beginning -- The legacy of Tamoxifen -- Appendix: Four decades of discovery in breast cancer research and treatment – an interview with V. Craig Jordan by Marc Poirot -- Selected Awards that Recognize the Contribution of Tamoxifen and Raloxifene to Medicine. |
|
|
|
|
|
|
|
|
Sommario/riassunto |
|
Tamoxifen is a pioneering medicine for the treatment and prevention of breast cancer. It is the first drug targeted therapy in cancer to be successful. Tamoxifen targets the tumor estrogen receptor. The therapy is known to have saved the lives of millions of women over the past 40 years. This monograph, written by V. Craig Jordan - known as the “father of tamoxifen” - and his Tamoxifen Team at the Georgetown University Washington DC, illustrates the journey of this milestone in medicine. It includes a personal interview with V. Craig Jordan about his |
|
|
|
|
|
|
|
|
|
|
|
|
|
four decades of discovery in breast cancer research and treatment. V. Craig Jordan was there for the birth of tamoxifen as he is credited for reinventing a “failed morning after contraceptive” to become the “gold standard” for the treatment of breast cancer. He contributed to every aspect of tamoxifen application in therapeutics and all aspects of tamoxifen’s pharmacology. He discovered the selective estrogen receptor modulators (SERMs) and explored the new biology of estrogen-induced apoptosis. |
|
|
|
|
|
|
2. |
Record Nr. |
UNINA9910962892003321 |
|
|
Autore |
Menken M. J. J |
|
|
Titolo |
2 Thessalonians / / Maarten J.J. Menken |
|
|
|
|
|
Pubbl/distr/stampa |
|
|
London ; ; New York, : Routledge, 1994 |
|
|
|
|
|
|
|
ISBN |
|
1-85684-193-6 |
1-134-86747-6 |
1-134-86748-4 |
1-282-77778-5 |
9786612777783 |
0-203-13306-4 |
|
|
|
|
|
|
|
|
Edizione |
[1st ed.] |
|
|
|
|
|
Descrizione fisica |
|
1 online resource (128p.) |
|
|
|
|
|
|
Collana |
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
Bibliographic Level Mode of Issuance: Monograph |
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references (p. [150]-155) and indexes. |
|
|
|
|
|
|
Nota di contenuto |
|
Introduction: 2 Thessalonians in historical perspective -- Chapter 2 Thessalonians in English translation -- Part 1 : The setting of 2 Thessalonians -- Chapter 2 The author of 2 Thessalonians -- Chapter 3 The milieu of 2 Thessalonians -- Part 2 : A commentary on 2 Thessalonians -- Chapter 4 The structure of 2 Thessalonians -- Chapter 2 Thessalonians 1: Prescript and proem : the eschatological retribution -- Chapter 2 Thessalonians 2: The body of the letter: the day of the Lord has not yet come -- Chapter 2 Thessalonians 3: Exhortation and letter-closing: the disorderly brothers and sisters -- |
|
|
|
|
|
|
|
|
|
|
|
|
|
Conclusion: 2 Thessalonians and Paul. |
|
|
|
|
|
|
Sommario/riassunto |
|
For all who desire tools for a deeper understanding of Scripture, this series presents a selection of works which have stood the test of time. This work explores key passages of the epistles to the Thessalonians. |
|
|
|
|
|
|
|
|
3. |
Record Nr. |
UNINA9910963271303321 |
|
|
Autore |
Ben-Ezer Gadi |
|
|
Titolo |
The Ethiopian Jewish exodus : narratives of the migration journey to Israel 1977-1985 / / Gadi BenEzer |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
London ; ; New York, : Routledge, 2002 |
|
|
|
|
|
|
|
ISBN |
|
1-134-48093-8 |
1-138-87015-3 |
1-134-48094-6 |
1-280-05037-3 |
0-203-21923-6 |
|
|
|
|
|
|
|
|
Descrizione fisica |
|
1 online resource (274 p.) |
|
|
|
|
|
|
Collana |
|
Routledge studies in memory and narrative ; ; 9 |
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
Jews - Ethiopia - History |
Jews - Ethiopia - Social life and customs |
Jews - Migrations |
Jews, Ethiopian - Israel - History |
Jews, Ethiopian - Israel - Social conditions - 20th century |
Immigrants - Israel - Social conditions - 20th century |
Social integration - Israel |
Ethiopia Emigration and immigration |
Israel Emigration and immigration |
|
|
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
Description based upon print version of record. |
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references (p. 225-246) and index. |
|
|
|
|
|
|
Nota di contenuto |
|
Book Cover; Title; Contents; List of illustrations; Acknowledgements; Note on transliteration and form; Maps; Introduction; The context of the journey; Interviewing and interpreting in cross-cultural research; The theme of Jewish identity; The theme of suffering; The theme of |
|
|
|
|
|
|
|
|
|
|
|
bravery and inner strength; The impact of the journey: psycho-social issues; Ethiopian Jews encounter Israel; Concluding remarks; Appendix; Notes; Bibliography; Index |
|
|
|
|
|
|
Sommario/riassunto |
|
Between 1977 and 1985, some 20,000 Ethiopian Jews left their homes in Ethiopia and - motivated by an ancient dream of returning to the land of their ancestors, 'Yerussalem' - embarked on a secret and highly traumatic exodus to Israel. Due to various political circumstances they had to leave their homes in haste, go a long way on foot through unknown country, and stay for a period of one or two years in refugee camps, until they were brought to Israel. The difficult conditions of the journey included racial tensions, attacks by bandits, night travel over mountains, incarceration, illness and de |
|
|
|
|
|
|
|
| |