1.

Record Nr.

UNINA9910961017203321

Titolo

Health effects of exposure to low levels of ionizing radiations : time for reassessment? / / Committee on Health Effects of Exposure to Low Levels of Ionizing Radiations, Board on Radiation Effects Research, Commission on Life Sciences, National Research Council

Pubbl/distr/stampa

Washington, D.C., : National Academy Press, 1998

ISBN

9786610186457

9780309173797

0309173795

9781280186455

1280186453

9780309580526

0309580528

9780585155760

0585155763

Edizione

[1st ed.]

Descrizione fisica

1 online resource (86 p.)

Collana

BEIR ; ; 7

The Compass series

Disciplina

616.9/897

Soggetti

Low-level radiation - Health aspects

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Nota di bibliografia

Includes bibliographical references (p. 51-72) and index.

Nota di contenuto

Health Effects of Exposure to Low Levels of Ionizing Radiations -- Copyright -- Preface -- Contents -- EXECUTIVE SUMMARY -- 1 INTRODUCTION -- 2 EPIDEMIOLOGIC INVESTIGATIONS -- NEW EPIDEMIOLOGIC RESULTS -- ADVANCES IN METHODOLOGY -- CONSIDERATIONS FOR A BEIR VII PHASE-2 COMMITTEE -- RADIOEPIDEMIOLOGIC TABLES -- 3 CELLULAR AND MOLECULAR CONSIDERATIONS -- DNA DAMAGE AND ITS REPAIR -- CONCLUSIONS -- CONDITIONED AND INDUCIBLE RESPONSES TO RADIATION -- CONCLUSIONS -- CHROMOSOMAL ABERRATIONS AND MUTATIONS -- Chromosomal Aberrations -- Mutations -- CONCLUSIONS -- 4 ANIMAL STUDIES -- CONCLUSIONS -- 5 RADIOBIOLOGIC PRINCIPLES AND RISK



MODELING -- LINEARITY VERSUS CURVILINEARITY -- THE DOSE DEPENDENCE OF RBE -- POTENTIAL IMPACT OF NEUTRONS -- CONCLUSIONS -- 6 MATHEMATICAL MODELS OF RADIATION CARCINOGENESIS -- THE TWO-MUTATION MODEL -- IMPLICATIONS OF THE MODEL FOR RISK ESTIMATION -- CONCLUSIONS -- LITERATURE CITED -- Information on Committee Members -- List of Acronyms -- ACKNOWLEDGMENTS.

Sommario/riassunto

The US Environmotection Agency Office of Radiation and Indoor Air asked the National Research Council to evaluate whether sufficient new data exist to warrant a reassessment of health risks reported in Health Effects of Exposure to Low Levels of Ionizing Radiations (BEIR V) in 1990. To respond to this request, the National Research Council assembled the Committee on Health Risks of Exposure to Low Levels of Ionizing Radiations. The work of the committee was conducted in what was called the BEIR VII phase-1 study. To assist the committee during its deliberations, various scientists were consulted for advice, and a workshop on the impact of biology on risk assessment was held in collaboration with the Department of Energy Office of Health and Environmental Research. The intent of the workshop was to address the implications of new understanding of the biologic basis of radiation injury and carcinogenesis for risk assessment.