1.

Record Nr.

UNINA9910959950603321

Titolo

The five series study : mortality of military participants in U.S. nuclear weapons tests : medical follow-up agency, Institute of Medicine / / by Susan Thaul ... [et al.] ; with oversight from the Committee to Study the Mortality of Military Personnel Present at Atmospheric Tests of Nuclear Weapons

Pubbl/distr/stampa

Washington, D.C., : National Academy Press, 2000

ISBN

9786610185658

9780309172592

0309172594

9781280185656

1280185651

9780309569392

0309569397

Edizione

[1st ed.]

Descrizione fisica

1 online resource (239 p.)

Altri autori (Persone)

ThaulSusan

Disciplina

616.9897

Soggetti

Nuclear weapons testing victims - Health aspects

Soldiers - Mortality

Nuclear weapons - Testing - Health aspects

Radiation carcinogenesis

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di contenuto

""The Five Series Study""; ""Copyright""; ""REVIEWERS""; ""Preface""; ""Acknowledgments""; ""Abbreviations, Acronyms, and Glossary""; ""Contents""; ""Summary""; ""METHODS""; ""FINDINGS AND DISCUSSION""; ""1 Study Rationale and Overview ""; ""RATIONALE""; ""BACKGROUND""; ""OVERVIEW""; ""2 Other Studies of Radiation Exposure of Military Personnel ""; ""INTRODUCTION""; ""MILITARY POPULATIONS""; ""3 An Overview of the U.S. Nuclear Weapons Testing Program ""; ""GREENHOUSE""; ""UPSHOT-KNOTHOLE""; ""CASTLE""; ""REDWING""; ""PLUMB BOB""; ""ESTIMATES OF EXTERNAL DOSES""; ""4 Data Sources ""



""COHORT IDENTIFICATION""""Nuclear Test Personnel Review Program""; ""National Archives and Military Collections""; ""CHARACTERISTICS OF COHORT MEMBERS, INCLUDING DATE OF BIRTH AND VITAL STATUS""; ""Beneficiary Identification and Records Locator Subsystem""; ""VA Master Index""; ""Military Personnel Folder""; ""CAUSE OF DEATH""; ""Veteran's Claim Folder""; ""National Death Index""; ""POPULATION MORTALITY RATES FOR COMPARISON""; ""5 The Participant Cohort ""; ""RELATIONSHIP OF PARTICIPANT ROSTERS USED IN THE 1985 PUBLICATION AND THIS REPORT""

""PARTICIPATION IN SERIES OTHER THAN THE SELECTION SERIES""""6 The Referent Cohort ""; ""7 Exposure Definition and Measurement ""; ""DNA-PROVIDED DOSE ESTIMATES""; ""Individual Doses""; ""Alternative Uses of Dose Data""; ""POTENTIAL SURROGATE MEASURES OF DOSE""; ""DECISIONS FOR THE ANALYSES IN THIS REPORT""; ""FUTURE OPTIONS FOR USE OF DOSIMETRY""; ""8 Mortality Ascertainment ""; ""FACT-OF-DEATH ASCERTAINMENT""; ""FACT-OF-DEATH VALIDATION""; ""DATE OF DEATH""; ""CAUSE-OF-DEATH ACQUISITION""; ""CAUSE-OF-DEATH VALIDATION""; ""9 Analysis Structure ""; ""OVERVIEW""; ""AVAILABLE DATA""

""ANALYSIS""""Variables""; ""Type of Analysis""; ""Diagnosis Groups""; ""10 Description of Cohort Characteristics ""; ""11 Findings ""; ""TESTS OF PREDETERMINED PRINCIPAL ENDPOINTS""; ""DESCRIPTIVE ANALYSES OF PREDETERMINED ADDITIONAL MORTALITY ENDPOINTS""; ""INVESTIGATING LEUKEMIA RISK BY LAND AND SEA SERIES PARTICIPATION""; ""INVESTIGATING LEUKEMIA RISK BY TIME SINCE FIRST PARTICIPATION AND AGE AT FIRST PARTICIPATION""; ""12 Discussion ""; ""LIMITATIONS""; ""Fact-of-Death and Cause-of-Death Ascertainment""; ""Statistical Power""; ""Other Possible Confounding Factors""

""Military Service Characteristics""""Other Lifetime Radiation Exposure""; ""Contributing and Associated Causes of Death""; ""Inadequate Dosimetry""; ""DISCUSSION""; ""Leukemia""; ""Thyroid Cancer""; ""Lung Cancer""; ""Nasal Cancer""; ""Prostate Cancer""; ""CONCLUDING COMMENTS""; ""References""; ""APPENDIX A A Review of the Dosimetry Data Available in the Nuclear Test Personnel Review Program""; ""APPENDIX B National Association of Atomic Veterans Medical Survey ""; ""APPENDIX C Epidemiology Primer ""; ""CHOICE OF COMPARISON GROUP""; ""FINE TUNING OF EXPOSED GROUP""; ""CONFOUNDERS""

""DATA COLLECTION""

Sommario/riassunto

More than 200,000 U.S. military personnel participated in atmospheric nuclear weapons tests between 1945 and the 1963 Limited Nuclear Test Ban Treaty. Questions persist, such as whether that test participation is associated with the timing and causes of death among those individuals. This is the report of a mortality study of the approximately 70,000 soldiers, sailors, and airmen who participated in at least one of five selected U.S. nuclear weapons test series1 in the 1950s and nearly 65,000 comparable nonparticipants, the referents. The investigation described in this report, based on more than 5 million person-years of mortality follow-up, represents one of the largest cohort studies of military veterans ever conducted.