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1. |
Record Nr. |
UNINA9910451324003321 |
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Autore |
Wodarz Dominik |
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Titolo |
Computational biology of cancer [[electronic resource] ] : lecture notes and mathematical modeling / / Dominik Wodarz and Natalia Komarova |
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Pubbl/distr/stampa |
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Hackensack, NJ, : World Scientific, 2005 |
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ISBN |
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1-281-89708-6 |
9786611897086 |
981-270-136-2 |
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Descrizione fisica |
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1 online resource (266 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Cancer - Mathematical models |
Cancer - Research |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Preface; Contents; Chapter 1 Cancer and somatic evolution; Chapter 2 Mathematical modeling of tumorigenesis; Chapter 3 Cancer initiation: one-hit and two-hit stochastic models; Chapter 4 Microsatellite and chromosomal instability in sporadic and familial cancers; Chapter 5 Cellular origins of cancer; Chapter 6 Costs and benefits of chromosomal instability; Chapter 7 DNA damage and genetic instability; Chapter 8 Tissue aging and the development of cancer; Chapter 9 Basic models of tumor inhibition and promotion; Chapter 10 Mechanisms of tumor neovascularization |
Chapter 11 Cancer and immune responsesChapter 12 Therapeutic approaches: viruses as anti-tumor weapons; Appendix A Exact formula for total probability of double mutations; Bibliography; Index |
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Sommario/riassunto |
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The book shows how mathematical and computational models can be used to study cancer biology. It introduces the concept of mathematical modeling and then applies it to a variety of topics in cancer biology. These include aspects of cancer initiation and progression, such as the somatic evolution of cells, genetic instability, and angiogenesis. The book also discusses the use of mathematical models for the analysis of therapeutic approaches such as chemotherapy, immunotherapy, and |
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the use of oncolytic viruses. |
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2. |
Record Nr. |
UNINA9910958961503321 |
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Autore |
Jolly Margaretta |
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Titolo |
In Love and Struggle : Letters in Contemporary Feminism / / Margaretta Jolly |
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Pubbl/distr/stampa |
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New York, NY : , : Columbia University Press, , [2008] |
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©2008 |
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ISBN |
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9786612872006 |
9781282872004 |
1282872001 |
9780231510752 |
0231510756 |
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Descrizione fisica |
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1 online resource (326 p.) |
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Collana |
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Gender and Culture Series |
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Disciplina |
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Soggetti |
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Feminists - Social networks - 20th century - Great Britain |
Feminists - History - 20th century - United States |
Feminism - History - 20th century |
Feminism - History |
Letter writing - History and criticism - Women authors |
Letters - Social aspects |
Electronic mail messages |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di contenuto |
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Front matter -- Contents -- Introduction. The Feminist World Of Love And Ritual -- PART I: Yours In Sisterhood -- 1. Love Letters to a New Me -- 2. Feminist Epistolary Romance -- 3. Velvet Boxing Gloves -- PART II: Letter Writing and the Ethics of Care -- 4. Theorizing Feminist Letters -- 5. Mothers and Daughters in Correspondence -- 6. Writing the Web: Letters from the Women's Peace Movement -- 7. Do Webs Work? Letters and the Clash of Communities -- PART III: The Right to |
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Be Cared For: Letters and the Life Cycle of a Social Movement -- 8. Care Versus Autonomy: The Problem of (Loving) Men -- 9. The Paradox of Care as a Right -- 10. How Different Is E-mail? -- 11. Care Ethics Online -- PART IV: The Afterlife of Letters -- 12. On Burning and Saving Letters -- 13. On Stealing Letters: The Ethics of Epistolary Research -- Conclusion -- Notes -- Bibliography -- Acknowledgments -- Index -- Backmatter |
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Sommario/riassunto |
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Winner of the 2009 Feminist and Women's Studies Association Book Prize Do you think I can be a feminist mother? Did I make you and your kisses up in my mind? Will you join our military protest at the gate? Will you feed the kids when I'm in prison? Are you able to forgive me for breaking off this correspondence because you are a man? During the women's movement of the 1970's and 1980's, feminists in the United States and Britain reinvented the image of the woman letter writer. Symbolically tearing up the love letter to an absent man, they wrote passionate letters to one another, exploring questions of sexuality, separatism, and strategy. These texts speak of the new interest women began to feel in one another and the new demands and disappointments these relationships would create. Margaretta Jolly provides the first cultural study of these letters, charting the evolution of feminist political consciousness from the height of the women's movement to today's e-mail networks. Jolly uncovers the passionate, contradictory emotions of both politics and letter writing and sets out the theory behind them as a fragile yet persistent ideal of care ethics, women's love, and epistolary art. She follows several compelling feminist relationships sustained through writing and confronts the mixed messages of the "open letter," which complicated political relations between women (such as Audre Lorde's "Open Letter to Mary Daly," which called out white feminists for their implicit racism).Jolly recovers the unsung literature of lesbianism and feminist romance, examines the ambivalent feelings within mother-daughter correspondences, and considers letter-writing campaigns during the peace movement. She concludes with a discussion of the ethical dilemma surrounding care versus autonomy and the meaning behind the burning or saving of letters. Letters that chart love stories, letters stowed away in attics, letters burnt at the end of romances, bittersweet letters written but never sent... this fascinating glimpse into women's intimate archives illuminates one of feminism's central concerns that all relationships are political and uniquely recasts a social movement in very emotional terms. |
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