1.

Record Nr.

UNINA9910958762503321

Titolo

Cancer and stem cells / / Thomas Dittmar and Kurt S. Zänker, editors

Pubbl/distr/stampa

New York, : Nova Biomedical Books, c2008

ISBN

1-61668-044-X

Edizione

[1st ed.]

Descrizione fisica

1 online resource (231 p.)

Altri autori (Persone)

DittmarThomas

ZänkerKurt S

Disciplina

616.99/4071

Soggetti

Cancer cells

Stem cells

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Cancer stem cells: a definition / Jichao Qin, Dean G. Tang -- Mathematical modeling of stem cells related to cancer / Monika Joanna Piotrowska ... [et al.] -- Where do cancer stem cells come from? / Calin Stoicov and JeanMarie Houghton -- Mismatch repair deficiencies and origin of cancer stem cells / Minal Garg -- Cancer stem cells in hematological malignancies / Aniruddha J. Deshpande and Christian Buske -- Stem cells in solid tumors / Andres Matoso and Alexander Yu. Nikitin -- Cancer stem cells and metastasis / Benjamin Tiede and Yibin Kang -- Exercise, stem cells, and cancer / Emre Tunca, Karsten Krüger, Frank C. Mooren -- Human adult stem cells as targets for cancer stem cells: evolution: OCT-4 gene and cell to cell communication / James E. Trosko -- Targeting cancer stem cells / Thomas Dittmar and Kurt S. Zänker.

Sommario/riassunto

Today, cancer is the second most prevelant cause of death, after heart disease, in the industrialized world. Till now, and despite promising results in cancer research, the primary cause of death in cancer is still 1: the formation of metastases at distant organs sites, 2: the presence of cancer cells that are resistant to current cancer therapies (chemotherapy/radiation) and which cause cancer relapse. Within the past three years it became evident that also solid tumor tissues contain a kind of stem cells, so-called cancer cells. These cancer stem cells have been described as chemo-/radiation therapy resistant tumor



initating cells. The purpose of this book is to summarize the latest findings about the role of stem cells in cancer.