1.

Record Nr.

UNINA9910957675503321

Titolo

Statins / / Gunnar N. Holmqvist (editor)

Pubbl/distr/stampa

New York, : Nova Science Publishers, c2008

ISBN

1-60876-345-5

Edizione

[1st ed.]

Descrizione fisica

1 online resource (219 p.)

Altri autori (Persone)

HolmqvistGunnar N

Disciplina

615/.718

Soggetti

Statins (Cardiovascular agents)

Anticholesteremic agents

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Statin therapy for coronary artery disease beyond lipid lowering effect / Teruo Inoue, Koichi Node -- Side effects of statins in monotherapy / Helmut Sinzinger, Bernhard A. Peskar -- Preliminary findings about the trends of the renal hemodynamics and the proxies of cardiovascular risk during a short course of atorvastatin therapy in essential hypertensives / Luigi Vernaglione -- Beneficial effects of addition of fenofibrate to statin therapy in patients with acute coronary syndrome after percutaneous coronary interventions / Hetal D. Shah ... [et al.] -- Non-lipid lowering effects of statins / A. Schmidt -- Statins in the therapy of acute coronary syndrome / Petr Ostadal -- Beneficial effects of addition of fenofibrate to statin therapy in patients with acute coronary syndrome after percutaneous coronary interventions / Hetal D. Shah ... [et al.] -- Bad HDL-C responders to statins / Dirk Devroey -- Beneficial effects of statins in systemic lupus erythematosus : molecular mechanism involved / Antonio G. Tristano.

Sommario/riassunto

This new book focuses on statins which are a relatively new group of drugs used to lower blood cholesterol levels. A high cholesterol level increases a person's risk of having a heart attack or stroke. The long-term use of statins reduces the risk of such an event and can increase the life expectancy of people with a history of heart disease. The statins work by blocking an enzyme in the body that is involved in the production of LDL cholesterol, especially in the liver. This enzyme is known as HMG coenzyme A reductase. The statins are the most



effective group of drugs for lowering the levels of LDL cholesterol in the body. Potential side-effects include muscle cramps and gastrointestinal upsets. These are usually resolved on temporarily lowering the dose. Liver enzyme derangements may occur, which generally return to normal after briefly discontinuing the drug. Some report headaches. Other side-effects occur rarely.