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1. |
Record Nr. |
UNINA9910455297903321 |
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Autore |
Hawley R. Scott |
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Titolo |
Advanced genetic analysis [[electronic resource] ] : finding meaning in a genome / / R. Scott Hawley and Michelle Y. Walker |
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Pubbl/distr/stampa |
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Malden, Mass., : Blackwell Pub., c2003 |
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ISBN |
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1-282-11830-7 |
9786612118302 |
1-4443-1308-8 |
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Descrizione fisica |
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1 online resource (257 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Genetics - Research - Methodology |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references (p. [220]-235) and indexes. |
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Nota di contenuto |
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Advanced Genetic Analysis; Contents; Preface; Introduction; 1: Mutation; 1.1 Types of mutations; 1.1.1 Muller's classification of mutants; 1.1.2 Modern mutant terminology; 1.1.3 DNA-level terminology; 1.2 Dominance and recessivity; 1.2.1 Dominance and recessivity at the level of the cell; 1.2.2 Difficulties in applying the terms ""dominant"" and ""recessive"" to sex-linked mutants; 1.3 The genetic utility of dominant and recessive mutants; Summary; Gallery of model organisms; 1.1 Our favorite organism: Drosophila melanogaster; 1.2 Our second favorite organism: Saccharomyces cerevisiae |
1.3 Our third favorite organism: Caenorhabditis elegans1.4 Our new favorite organism: zebrafish; 1.5 Phage lambda; 1.6 Phage T4; 1.7 Arabidopsis thaliana; 1.8 Mus musculus (the mouse); 2: Mutant hunts; 2.1 Why look for new mutant?; 2.1.1 Reason 1: To identify genes required for a specific biological process; Box 2.1 A screen for embryonic lethal mutations in Drosophila; Box 2.2 The balancer chromosome; 2.1.2 Reason 2: To isolate more mutations in a specific gene of interest; Box 2.3 A screen for sex-linked lethal mutations in Drosophila |
2.1.3 Reason 3: To obtain mutation tools for structure-function analysis2.1.4 Reason 4: To isolate mutations in a gene so far identified only by molecular approaches; 2.2 Mutagenesis and mutational |
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mechanisms; 2.2.1 Method 1: Ionizing radiation (usually X-rays and gamma-rays); 2.2.2 Method 2: Chemical mutagens; 2.2.3 Method 3: Transposons as mutagens; 2.2.4 Method 4: Targeted gene disruption (a variant on transposon mutagenesis); Box 2.4 Making phenocopies by RNAi and co-suppression; 2.3 What phenotype should you screen (or select) for?; 2.4 Actually getting started |
2.4.1 Your starting material2.4.2 Pilot screens; 2.4.3 Keeping too many, keeping too few; 2.4.4 How many mutants is enough?; Summary; Box 2.5 Reviews of mutant isolation schemes and techniques in various organisms; 3: The complementation test; 3.1 The essence of the complementation test; Box 3.1 A more rigorous definition of the complementation test; Box 3.2 An example of using the complementation test in yeast; 3.2 Rules for using the complementation test; Box 3.3 Transformation rescue is a variant of the complementation test |
Box 3.4 One method for determining whether or not a dominant mutation is an allele of a given gene, or how to make dominants into recessives by pseudo-reversion3.3 How might the complementation test lie to you?; 3.4 Second-site non-complementation (SSNC) (non-allelic non-complementation); 3.4.1 Type I SSNC (poisonous interactions): the interaction is allele-specific at both loci; Box 3.5 Pairing-dependent complementation: transvection; Box 3.6 Synthetic lethality and genetic buffering; 3.4.2 Type 2 SSNC (sequestration): the interaction is allele-specific at one locus |
3.4.3 Type 3 SSNC (combined haplo-insufficiency): the interaction is allele-independent at both loci |
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Sommario/riassunto |
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Advanced Genetic Analysis brings a state-of-the-art, exciting new approach to genetic analysis. Focusing on the underlying principles of modern genetic analysis, this book provides the 'how' and 'why' of the essential analytical tools needed. The author's vibrant, accessible style provides an easy guide to difficult genetic concepts, from mutation and gene function to gene mapping and chromosome segregation. Throughout, a balanced range of model organisms and timely examples are used to illustrate the theoretical basics. Basic principles - Focuses students attention on t |
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2. |
Record Nr. |
UNINA9910956248103321 |
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Titolo |
TMR research in insulating granular magnetic materials / / Shigeo Honda ... [et al.], editors |
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Pubbl/distr/stampa |
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New York, : Nova Science Publishers, c2012 |
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ISBN |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (149 p.) |
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Collana |
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Materials science and technologies |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Electric insulators and insulation - Materials |
Granular materials - Electric properties |
Magnetic films |
Magnetoresistance |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Intro -- TMR RESEARCH IN INSULATING GRANULAR MAGNETIC MATERIALS -- TMR RESEARCH IN INSULATING GRANULAR MAGNETIC MATERIALS -- CONTENTS -- PREFACE -- GIANT MAGNETORESISTANCE IN MAGNETIC MULTILAYERS AND MAGNETIC GRANULAR ALLOYS -- 1A. METALLIC MAGNETIC MULTILAYERS -- 1. Introduction -- 1.1. Magnetic Metal Multilayers -- 1.2. Giant Magnetoresistance -- 2. Experimental -- 3. Survey of Results -- 3.1. As-deposited Multilayers -- 3.2. Annealing Effect -- 4. Summary -- 1B. GRANULAR METALLIC FILMS -- 1. Introduction -- 2. Experimental -- 3. Survey of the Results -- 3.1. As-deposited State -- 3.2. Annealing Effect -- CONCLUSION -- REFERENCES -- TUNNELING GIANT MAGNETORESISTANCE IN HETEROGENEOUS INSULATING GRANULAR FILMS AND MAGNETIC GRANULAR ALLOYS -- 1. INTRODUCTION -- 2. EXPERIMENTAL -- 3. ELECTRICAL TRANSPORTAT IN HETEROGENEOUS INSULATING GRANULAR FILMS -- 4. MAGNETIC PROPERTIES -- 5. TUNNELING MAGNETORESISTANCE -- CONCLUSION -- REFERENCES -- FORMATION OF GRANULAR LAYERS BY ION IMPLANTATION -- 1. INTRODUCTION -- 2. EXPERIMENTAL DETAILS FOR CHARACTERIZING TMR GRANULES -- 3. ION IMPLANTATION -- 3.1. Single Ion Implantation -- 3.2. Multiple Ion Implantation -- 3.3. Modification of Implanted Granules by High Energy Ion Irradiation -- CONCLUSION -- REFERENCES -- TMR EFFECT IN |
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GRANULAR LAYERS BY ION IMPLANTATION -- 1. INTRODUCTION -- 2. EXPERIMENTAL TECHNIQUES FOR CHARACTERIZING TMR GRANULES -- 3 MAGNETIC PROPERTIES AND TMR EFFECTS IN IMPLANTED GRANULES -- 3.1. Direct Implantation of Magnetic Elements -- 3.2. Ion Beam Modification of TMR Effect -- CONCLUSION -- ACKNOWLEDGMENTS -- REFERENCES -- INDEX. |
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Sommario/riassunto |
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Artificially structured materials granular magnetic solids, as well as nano-sized multi-layer films are of great interest. The granules consist of nanometer sized metal particles embedded in an immiscible medium, in most cases an insulator. This book presents and reviews research in the study of insulating granular magnetic materials. |
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