Molecular system bioenergetics : energy for life / / edited by Valdur Saks

• Record Nr.: UNINA9911019723203321
• Pubbl/distr/stampa: Weinheim, : Wiley-VCH, c2007
• ISBN: 9786611311827; 9781281311825; 1281311820; 9783527621095; 3527621091; 9783527621101; 3527621105
• Descrizione fisica: 1 online resource (635 p.)
• Altri autori (Persone): SaksV. A
• Disciplina: 572.431
• Soggetti: Bioenergetics; Cell metabolism; Energy metabolism
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Molecular System Bioenergetics; Contents; Preface; List of Contributors; Introduction: From the Discovery of Biological Oxidation to Molecular System Bioenergetics; References; Part I Molecular System Bioenergetics: Basic Principles, Organization, and Dynamics of Cellular Energetics; 1 Cellular Energy Metabolism and Integrated Oxidative Phosphorylation; Abstract; 1.1 Introduction; 1.2 Membrane Transport and Initial Activation; 1.3 Cytosolic Pathway; 1.4 Mitochondrial Transport and Metabolism; 1.5 Respiratory Chain and Oxidative Phosphorylation; 1.6 Electron Supply; 1.7 Reducing Power Shuttling Across the Mitochondrial Membrane1.8 Electron Transfer in the Respiratory Chain: Prominent Role of Complex I in the Regulation of the Nature of Substrate; 1.9 Modulation of Oxidative Phosphorylation by Respiratory Chain Slipping and Proton Leak; 1.10 The Nature of Cellular Substrates Interferes with the Metabolic Consequences of Uncoupling; 1.11 Dynamic Supramolecular ; Arrangement of Respiratory Chain and Regulation of Oxidative Phosphorylation; References; 2 Organization and Regulation of Mitochondrial Oxidative Phosphorylation; Abstract; 2.1 Introduction; 2.2 Oxidative Phosphorylation and the Chemiosmotic Theory2.3 The Various Mechanisms of Energy Waste; 2.3.1 Passive Leak; 2.3.2 Leak Catalyzed by Uncoupling Proteins; 2.3.3 The Active Leak; 2.3.4 The Slipping Mechanism; 2.4 Mechanisms of Coupling in Proton Pumps; 2.5 Oxidative Phosphorylation Control and Regulation; 2.5.1 Metabolic Control Analysis; 2.5.2 Regulations; 2.5.2.1 Kinetic Regulation of Mitochondrial Oxidative Phosphorylation: Complex I Covalent cAMP-dependent Phosphorylation; 2.5.2.2 Cytochrome Oxidase: An Example of Coordinate Regulation; 2.6 Supramolecular Organization of the Respiratory Chain2.6.1 Structural Data; 2.6.1.1 ATP Synthase Organization; 2.6.1.2 Respiratory Chain Supramolecular Organization; 2.6.2 Functional Data; 2.7 Conclusions; References; 3 Integrated and Organized Cellular Energetic Systems: Theories of Cell Energetics, Compartmentation, and Metabolic Channeling; Abstract; 3.1 Introduction; 3.2 Theoretical Basis of Cellular Metabolism and Bioenergetics; 3.2.1 Thermodynamic Laws, Energy Metabolism, and Cellular Organization; 3.2.2 Chemical and Electrochemical Potentials: Energy of Transmembrane Transport and Metabolic Reactions3.2.3 Non-equilibrium, Steady-state Conditions; 3.2.4 Free Energy Changes and the Problem of Intracellular Organization of Metabolism; 3.2.5 Macromolecular Crowding, Heterogeneity of Diffusion, Compartmentation, and Vectorial Metabolism; 3.2.5.1 Heterogeneity of Intracellular Diffusion and Metabolic Channeling; 3.2.5.2 Compartmentation Phenomenon and Vectorial Metabolism; 3.3 Compartmentalized Energy Transfer and Metabolic Sensing; 3.3.1 Compartmentation of Adenine Nucleotides in Cardiac Cells
• Sommario/riassunto: In this first integrated view, practically each of the world's leading experts has contributed to this one and only authoritative resource on the topic. Bringing systems biology to cellular energetics, they address in detail such novel concepts as metabolite channeling and medical aspects of metabolic syndrome and cancer.

Bourgeois nightmares : suburbia, 1870-1930 / / Robert M. Fogelson

• Record Nr.: UNINA9910954290103321
• Autore: Fogelson Robert M
• Pubbl/distr/stampa: New Haven, : Yale University Press, c2005
• ISBN: 9786611740597; 9781281740595; 1281740594; 9780300126990; 0300126999
• Edizione: [1st ed.]
• Descrizione fisica: 1 online resource (272 p.)
• Disciplina: 307.76/0973
• Soggetti: Suburbs - United States - History; Real covenants - United States; Suburban life - United States - History
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Bibliographic Level Mode of Issuance: Monograph
• Nota di bibliografia: Includes bibliographical references (p. 213-253) and index.
• Nota di contenuto: Suburbia, 1870-1930 : the quest for permanence -- Bourgeois nightmares : fears of almost everyone and everything.
• Sommario/riassunto: The quintessential American suburbs, with their gracious single-family homes, large green lawns, and leaf-shaded streets, reflected not only residents' dreams but nightmares, not only hopes but fears: fear of others, of racial minorities and lowincome groups, fear of themselves, fear of the market, and, above all, fear of change. These fears, and the restrictive covenants that embodied them, are the subject of Robert M. Fogelson's fascinating new book.As Fogelson reveals, suburban subdividers attempted to cope with the deep-seated fears of unwanted change, especially the encroachment of "undesirable" people and activities, by imposing a wide range of restrictions on the lots. These restrictions ranged from mandating minimum costs and architectural styles for the houses to forbidding the owners to sell or lease their property to any member of a host of racial, ethnic, and religious groups. These restrictions, many of which are still commonly employed, tell us as much about the complexities of American society today as about its complexities a century ago.