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Record Nr. |
UNINA9910901890203321 |
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Titolo |
Exploring and exploiting genetic risk for psychiatric disorders / / edited by Joshua A. Gordon and Elisabeth B. Binder |
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Pubbl/distr/stampa |
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Cambridge, Massachusetts : , : The MIT Press, , [2023] |
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ISBN |
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9780262377423 |
026237742X |
9780262377430 |
0262377438 |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (353 pages) |
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Collana |
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Strüngmann forum reports |
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Disciplina |
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Soggetti |
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Mental illness - Genetic aspects |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Intro -- Contents -- List of Contributors -- Preface -- 1: Exploring and Exploiting Genetic Risk for Psychiatric Disorders -- Gene Discovery -- 2: Delineating Additional Risk Factors -- 3: Data Collection -- 4: Environmental Risk and Gene-Environment Relationships in Psychiatric Disorders -- Understanding Rare Variation -- 5: Rare Variants -- 6: Promises and Challenges of Precision Medicine in Rare Neurodevelopmental Disorders -- 7: Experimental Model Systems for Rare and Common Variants -- Understanding Common Variation -- 8: Common Alleles -- 9: Hypotheses of How Common Variants Create Risk for Psychiatric Disorders -- 10: From Common Variant to Function -- 11: Contextualizing Convergent Common Variant Mechanisms through Systems Biology -- Clinical Considerations -- 12: Maximizing Near-Term Clinical Opportunities for Psychiatric Genetics -- 13: The Use of Polygenic Risk Scores in Clinical Psychiatry -- 14: Ethical Challenges Associated with Advances in Genetic Prediction of Neuropsychiatric Disorders -- 15: Psychiatric Genetic Counseling -- 16: Concluding Summary -- Bibliography -- Subject Index -- Strüngmann Forum Report Series. |
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Sommario/riassunto |
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"This volume examines the state of psychiatric genetics and charts a path forward for further discovery and translation"-- |
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