1.

Record Nr.

UNINA9910890193403321

Autore

Vaschetto Luis M

Titolo

miRNAs, Human Health and Diseases / / edited by Luis M. Vaschetto

Pubbl/distr/stampa

Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024

ISBN

3-031-64788-2

Edizione

[1st ed. 2024.]

Descrizione fisica

1 online resource (381 pages)

Collana

Epigenetics and Human Health, , 2191-2270 ; ; 13

Disciplina

572.865

Soggetti

Epigenetics

Genetics

Molecular genetics

Cancer - Genetic aspects

Genetics and Genomics

Molecular Genetics

Cancer Genetics and Genomics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Chapter 1. MiRNomics: An Introduction to MicroRNA Biology -- Chapter 2. MicroRNA Databases -- Chapter 3. Bioinformatics Tools to Study the Role of miRNAs -- MicroRNAs as Promising Therapeutic Targets -- Chapter 4. MicroRNAs as Promising Therapeutic Targets -- Chapter 5. The Interplay Between MicroRNAs and Genetic Diseases -- Chapter 6. Circulating miRNAs as Biomarkers for Early Disease Diagnosis -- Chapter 7. miRNAs as Biomarkers for Neurodegenerative Diseases -- Chapter 8. MicroRNAs and Immune-Related Disorders -- Chapter 9. MicroRNAs and Cardiovascular Diseases -- Chapter 10. miRNAs in Aging -- Chapter 11. MicroRNAs in Viral Infection -- Chapter 12. Inter-Kingdom Signalling: Exploring the Relationships among Microorganisms and microRNAs in Human Health.

Sommario/riassunto

This new volume of the book series Epigenetics and Human Health is dedicated to microRNAs (miRNAS), regulatory non-coding RNAs that have important roles in the control of gene expression both at posttranscriptional and transcriptional levels. Endogenous miRNAs regulate gene expression patterns in a sequence-specific manner. These short sequences may serve as potential therapeutic targets in the



treatment of complex diseases including cancer, cardiovascular diseases, neurocognitive disorders, respiratory diseases and pathogenic infections. Moreover, miRNAs hold promise to be used as extensive diagnostic and prognostic markers of disease. miRNAs, Human Health and Disease is an essential reading for graduate and undergraduate students, researchers, and academics interested in the latest developments on non-coding RNA-mediated pathways associated with health and disease.