1.

Record Nr.

UNINA9910783412003321

Titolo

Free radicals and diseases : gene expression, cellular metabolism and pathophysiology / / edited by Tilman Grune

Pubbl/distr/stampa

Amsterdam ; ; Oxford : , : IOS Press, , 2005

©2005

ISBN

1-280-50485-4

9786610504855

1-4294-0199-0

1-60750-118-X

600-00-0430-3

1-60129-099-3

Descrizione fisica

1 online resource (viii, 193 pages) : illustrations

Collana

NATO science series. Series I, Life and behavioural sciences, , 1566-7693 ; ; v. 367

Altri autori (Persone)

GruneTilman

Disciplina

616.07

Soggetti

Free radicals (Chemistry) - Pathophysiology

Active oxygen - Pathophysiology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Title page; Preface; Contents; DNA Lesions as Biomarkers of Inflammation and Oxidative Stress: A Preliminary Evaluation; Lipid Peroxidation Measurements - Methodological Approaches and Clinical Importance; Role of Oxidative Stress in Aging of the Yeast Saccharomyces cerevisiae; mtNOS: Regulation by Mitochondrial Membrane Potential; Mutliplicity of Mitochondrial Functioning; ROS-Induced Oscillations of Mitochondrial Transmembrane Potential in Cultured Rat Astocytes; The Effects of Nitric Oxide and Peroxynitrite on MnSOD (E. coli)

The Proteasomal Degradation System and Its Role During Oxidative Stress; Peptide Methionine Sulfoxide Reductases in Aging and Oxidative Stress; Activation of Microglial Proteolysis; Vitamin E Metabolism; Significance of the alpha-Tocopherol Salvage Pathway; Induction and Inhibition of Apoptotic Pathways by Hydrogen Peroxide; Photooxidative Processes in Skin: From Damage to Signaling; Role of Cholesterol or



Homocysteine in the Development of Atherosclerosis: Effect of Vitamin E; Different Roles of Nitric Oxide in Regulation of Interscapular Brown Adipose Tissue Hyperplasia; Adaptation to Exercise-Induced Oxidative Stress; Clinical Use of Carotenoids - Antioxidative Protection versus Prooxidative Side Effects; Author Index

Sommario/riassunto

This publication contains an extensive overview of free radicals and diseases, including both basic science approaches and clinical applications. The research of the last decades has contributed substantially to the understanding role and function of these metabolites. It is the aim of the editors to include a large variety of biological models ranging from yeast over mitochondria, isolated cells and cell culture models to animals and humans. The topics discussed focus on the function and integrity of mitochondria under oxidative conditions, the role of protein oxidation and proteolysis in the

2.

Record Nr.

UNINA9910887837703321

Titolo

JoVE science education Lab safety

Pubbl/distr/stampa

Cambridge, Massachusetts : , : MyJoVE Corporation, , [2014]-

Descrizione fisica

1 online resource (streaming video files)

Disciplina

570.72

Soggetti

Laboratories

Chemicals - Safety measures

Science - Study and teaching

Biology - Experiments

Safety - Experiments

Safety

Safety - Study and teaching

Streaming video

Film clips.

Internet videos.

Nonfiction films.

Video recordings.

Lingua di pubblicazione

Inglese

Formato

Videoregistrazione



Livello bibliografico

Periodico

Note generali

Refereed/Peer-reviewed

From the publisher: "This collection provides safety guidelines to be followed when working with hazardous materials and equipment. It covers universal topics such as PPE, electrical safety, and general emergency guidelines, as well as some specific safety procedures for chemistry and biology laboratories."

Includes video as well as abstracts and transcripts (in both HTML and PDF formats).

Sommario/riassunto

This collection provides an introduction to the field of lab safety.