1.

Record Nr.

UNINA9910887000603321

Autore

Mayevsky Avraham

Titolo

The Mongolian Gerbil Brain : Mitochondrial Function, Vasculature, and Pathophysiological States / / by Avraham Mayevsky

Pubbl/distr/stampa

Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024

ISBN

3-031-69549-6

Edizione

[1st ed. 2024.]

Descrizione fisica

1 online resource (341 pages)

Disciplina

599.3233

Soggetti

Neurosciences

Nervous system - Diseases

Physiology

Medical sciences

Drug development

Medicine - Research

Biology - Research

Neuroscience

Neurological Disorders

Animal Physiology

Preclinical Research

Biomedical Research

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Chapter 1 Historical Background of the Mongolian Gerbil in Research -- Chapter 2 Brain Energy Metabolism and mitochondrial function -- Chapter 3 Brain Real Time Monitoring systems used in Gerbils -- Chapter 4 Brain vasculature in the Mongolian Gerbil's -- Chapter 5 Brain Multisite recording under brain perturbations -- Chapter 6 Multiparametric Responses to Brain Oxygen Supply -- Chapter 7 Multiparametric Responses to Brain Activation -- Chapter 8 Neuroprotactants effect on the Gerbil Brain -- Chapter 9 Discussion and Conclusions.

Sommario/riassunto

The Mongolian gerbil brain lies in the anatomy of the blood vessels supplying blood to the brain. In all mammals, there is a special



mechanism that compensates for the decreased blood flow to the brain in the case of development of stroke. This mechanism is missing in the gerbil and therefore makes the Mongolian gerbil a unique model for stroke. Dr. Mayevsky adopted the gerbil as a model for stroke and his laboratory uniquely studied the mitochondria in the gerbil brain under various pathophysiological conditions. This book describes the history of the Mongolian gerbil in research, the brain energy metabolism and mitochondrial function and brain real-time monitoring systems used in gerbils, as well as the brain vasculature of the Mongolian gerbil. Further, the book includes chapters on brain multisite recording under brain perturbations, multiparametric responses to brain activation, and the effect of neuroprotectants on the gerbil brain. This is an ideal book for research teams researching stroke and epilepsy.