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Record Nr. |
UNINA9910877808103321 |
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Titolo |
The epigenome : molecular hide and seek / / edited by S. Beck and A. Olek |
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Pubbl/distr/stampa |
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Weinheim ; ; [Cambridge], : Wiley-VCH, c2003 |
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ISBN |
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1-280-52085-X |
9786610520855 |
3-527-60597-5 |
3-527-60151-1 |
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Descrizione fisica |
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1 online resource (190 p.) |
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Altri autori (Persone) |
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OlekA (Alexander) |
BeckStephan (Stephan G.) |
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Disciplina |
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Soggetti |
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Human genome |
Medical genetics |
Nature and nurture |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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The Epigenome Molecular Hide and Seek; Preface; Contents; 1 Five Not Four: History and Significance of the Fifth Base; Summary; 1.1 Historical Introduction; 1.2 Sequencing 5-methylcytosine (5-mC) Residues in Genomic DNA; The Bisulfite Method; 1.3 Gene Silencing; 1.4 Development; 1.5 Abnormal DNA Methylation in Cancer Cells; 1.6 Nuclear Transfer; 1.7 Aging; 1.8 The Future; References; 2 (Epi)genetic Signals: Towards a Human Genome Sequence of All Five Nucleotides; Summary; 2.1 A Linguistic Prologue; 2.2 Towards the Complete Sequence of the Human Genome with Five Nucleotides |
2.3 Patterns of DNA Methylation - the Scaffold for Building a Functional Genome2.4 DNA Methylation Patterns in Segments of the Human Genome and in Viral Genomes; 2.4.1 On Viral Genomes and Foreign DNA Integrates (Table 2.1); 2.4.2 DNA Methylation Patterns in the Human Genome (Table 2.1); 2.5 Insertions of Foreign DNA into Established Mammalian Genomes; 2.6 De Novo Methylation of Integrated Foreign DNA; 2.6.1 Ad12 Genomes in Hamster Tumor Cells; |
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