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Record Nr. |
UNINA9910877299503321 |
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Titolo |
The Biology of hyaluronan / / [editors: David Evered and Julie Whelan.] |
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Pubbl/distr/stampa |
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Chichester, UK ; ; New York, : Wiley, 1989 |
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ISBN |
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1-282-34760-8 |
9786612347603 |
0-470-51377-2 |
0-470-51378-0 |
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Descrizione fisica |
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1 online resource (312 p.) |
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Collana |
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Ciba Foundation symposium ; ; 143 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Hyaluronic acid - Physiological effect |
Physiology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Based on a "Symposium on the Biology of Hyaluronan, held at the Ciba Foundation, London, 27-29 September 1988." |
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Nota di bibliografia |
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Includes bibliographies and index. |
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Nota di contenuto |
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THE BIOLOGY OF HYALURONAN; Contents; Participants; Introduction; Secondary structures in hyaluronan solutions: chemical and biological implications; Identification and regulation of the eu karyotic hyaluronate synthase; Turnover and metabolism of hyaluronan; Enzymic pathways of h yal u ronan catabolism; The interaction of hyaluronate with the cell surface: the hyalu ronate receptor and the core protein; H yaluronan and hyalu ronan- binding proteins in cartilaginous tissues; The role of a cell-associated hyaluronan- binding protein in fibroblast behaviour |
Hyaluronate-cell interactions and growth factor regulation of hyaluronate synthesis during limb developmentThe role and tu rnou r-assoc regulation of ated hyaluronan; Interactions between cells of the immune system and hyaluronate synthesis by human dermal fibroblasts; Hyaluronan and angiogenesis; Hyaluronan and hyaluronectin in the nervous system; Changes in hyaluronan concentration in tissues and body fluids in disease states; The specific interaction between fibrin(ogen) and hyaluronan: possible |
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consequences in haemostasis, inflammation and wound he; Clinical uses of hyaluronan |
General discussionsumming-UP; Index of contributors; Subject index |
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Sommario/riassunto |
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Presents state-of-the-art applications in hyaluronan research, from hyaluronan's physicochemical properties to its clinical role as a connective tissue marker and its surgical implications, particularly in ear, eye and orthopaedic surgery. Covers hyaluronan's synthesis and catabolism, its role in cells, its interactions with specific binding proteins, and its role in the embryonic nervous system. |
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