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Record Nr. |
UNINA9910877188803321 |
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Autore |
Vauquelin Georges |
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Titolo |
G protein-coupled receptors : molecular pharmacology from academic concept to pharmaceutical research / / Georges Vauquelin, Bengt von Mentzer |
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Pubbl/distr/stampa |
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Chichester, England ; ; Hoboken, NJ, : John Wiley & Sons, c2007 |
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ISBN |
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1-282-34870-1 |
9786612348709 |
0-470-51665-8 |
0-470-51664-X |
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Descrizione fisica |
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1 online resource (266 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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G proteins - Receptors |
Molecular pharmacology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references (p. [235]-243) and index. |
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Nota di contenuto |
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Chemical messengers and the cell membrane -- Radioligand binding studies -- Functional studies -- G protein-coupled receptors -- Concluding remarks. |
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Sommario/riassunto |
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G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging from cell-cell communication processes to physiological responses. They play an important role in a variety of diseases from cancer and diabetes, to neurodegenerative, inflammatory and respiratory disorders. GPCRs are therefore of utmost interest in drug development: over half of all prescription drugs currently on the market act by targeting these receptors directly or indirectly. G Protein-coupled Receptors: Molecular Pharmacology provi |
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