1.

Record Nr.

UNINA9910877027603321

Titolo

Role of lipid excipients in modifying oral and parenteral drug delivery : basic principles and biological examples / / edited by Kishor M. Wasan

Pubbl/distr/stampa

Hoboken, N.J., : Wiley-Interscience, c2007

ISBN

1-280-65456-2

9786610654567

0-470-09798-1

0-470-09797-3

Descrizione fisica

1 online resource (217 p.)

Altri autori (Persone)

WasanKishor M

Disciplina

615/.7

Soggetti

Lipids - Therapeutic use

Excipients

Drugs - Dosage forms

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

ROLE OF LIPID EXCIPIENTS IN MODIFYING ORAL AND PARENTERAL DRUG DELIVERY; CONTENTS; PREFACE; CONTRIBUTORS; CHAPTER 1 INTERACTION OF DRUG TRANSPORTERS WITH EXCIPIENTS; CHAPTER 2 FORMULATION ISSUES AROUND LIPID-BASED ORAL AND PARENTERAL DELIVERY SYSTEMS; CHAPTER 3 LIPID-BASED PARENTERAL DRUG DELIVERY SYSTEMS: BIOLOGICAL IMPLICATIONS; CHAPTER 4 PRINCIPLES IN THE DEVELOPMENT OF INTRAVENOUS LIPID EMULSIONS; CHAPTER 5 PROTEIN ADSORPTION PATTERNS ON PARENTERAL LIPID FORMULATIONS: KEY FACTOR DETERMINING THE IN VIVO FATE; CHAPTER 6 NANOPARTICLE TARGETING FOR DRUG DELIVERY ACROSS THE BLOOD-BRAIN BARRIER

CHAPTER 7 LIPID-COATED PERFLUOROCARBON STRUCTURES AS PARENTERAL THERAPEUTIC AGENTSINDEX

Sommario/riassunto

This comprehensive resource covers the fundamentals, formulation, and biopharmaceutical issues of lipid-based drug delivery. It presents the principles of lipid absorption and covers formulation issues, such as dissolution testing and stability testing, and physiological and biopharmaceutical issues, including the role of specific enzymes, the



evaluation of transport systems in the body, and the mechanisms governing the transport of water-insoluble drugs.