1.

Record Nr.

UNINA9910876910603321

Titolo

Aluminum in biology and medicine

Pubbl/distr/stampa

Chichester [England] ; ; New York, : Wiley, 1992

ISBN

1-282-34780-2

9786612347801

0-470-51430-2

0-470-51431-0

Edizione

[1st ed.]

Descrizione fisica

1 online resource (336 p.)

Collana

Ciba Foundation symposium ; ; 169

Altri autori (Persone)

ChadwickDerek

WhelanJulie

Disciplina

612/.01524

Soggetti

Aluminum - Physiological effect

Aluminum - Pathophysiology

Alzheimer's disease - Pathophysiology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Editors, Derek J. Chadwick (organizer) and Julie Whelan.

"A Wiley-Interscience publication."

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

ALUMINIUM IN BIOLOGY AND MEDICINE; Contents; Aluminium in biology: an introduction; Aluminium speciation in biology; Dietary and other sources of aluminium intake; The interrelationship between silicon and aluminium in the biological effects of aluminium; The epidemiology of Alzheimer's disease in relation to aluminium; Aluminium and the pathogenesis of Alzheimer's disease: a summary of evidence; Intestinal absorption of aluminium; Aluminium intoxication in renal disease; Aluminium and Alzheimer's disease

Aluminium accumulation, B-amyloid deposition and neurofibrillary changes in the central nervous systemAluminium(III) in experimental cell pathology; Elemental analysis of neurofibrillary tangles in Alzheimer's disease using proton-induced X-ray analysis; Aluminium and the neurofibrillary tangle: results of tissue microprobe studies; Intracellular effects of aluminium on receptor-activated cytoplasmic Ca2+ signals in pancreatic acinar cells; Neurotoxic effects of dietary aluminium

Molecular characterization and measurement of Alzheimer's disease



pathology: implications for genetic and environmental aetiologySumming-up; Index of contributors; Subject index

Sommario/riassunto

Prominent contributors address issues regarding the toxicity of aluminum which causes an encephalopathy in renal dialysis patients and is also known to damage animals and plants via acid rain. Examines the chemistry and biology of aluminum compounds focusing on the evidence for and against aluminum's role in Alzheimer's disease.