1.

Record Nr.

UNINA9910865292103321

Autore

Prabhakar Hemanshu

Titolo

Principles and Practice of Neurocritical Care

Pubbl/distr/stampa

Singapore : , : Springer, , 2024

©2024

ISBN

981-9980-59-3

Edizione

[1st ed.]

Descrizione fisica

1 online resource (839 pages)

Altri autori (Persone)

SinghalVasudha

ZirpeKapil G

SapraHarsh

Disciplina

616.80428

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Intro -- Preface -- Acknowledgments -- Contents -- Part I: History of Neurocritical Care -- 1: Introduction to Neurocritical Care -- References -- Part II: Basic Principles of Neurocritical Care -- 2: Neurological Examination in Neurocritical Care -- 2.1  Introduction -- 2.2  The ABCDE (Airway, Breathing, Circulation, Disability, Exposure) Approach and the ABCGS (Airway, Breathing, Circulation, Glucose, or Seizures) Approach -- 2.2.1  Initial Assessment -- 2.2.2  History and General Examination -- 2.2.3  Neurological Examination of a Conscious Patient -- Neurological Examination of a Patient with an Altered Sensorium -- 2.2.4  Neurological Examination of a Patient in a Coma -- 2.3  Examination of Cranial Nerves (CNs) [5, 11] -- 2.3.1  Motor Functions and Assessment -- 2.3.2  Reflex Examination -- Upper Motor vs. Lower Motor Neuron Disease -- 2.3.3  Motor Examination in an Unconscious Patient -- 2.3.4  Sensory Testing -- 2.3.5  Pupillary Size and Reflex -- 2.3.6  Brainstem Reflexes -- 2.3.7  Neuroexamination in Pediatrics -- References -- 3: Cerebrospinal Fluid Dynamics -- 3.1  Introduction -- 3.2  CSF-Containing Spaces [4] -- 3.3  CSF Production -- 3.3.1  From the Choroid Plexus (CP) -- The Role of Ion Channels in CSF Secretion from the CP -- Ion Transport -- 3.3.2  Extra-Choroidal CSF Formation -- Movement of Glucose -- Movement of Proteins -- 3.4  CSF



Composition -- 3.5  Continuity between the Ventricular CSF and the Brain ECS -- 3.6  The Role of the Glymphatic System -- 3.7  CSF Flow -- 3.8  CSF Reabsorption -- 3.8.1  Meningeal Lymphatics -- 3.8.2  Continuous Fluid Exchange [13] -- 3.9  CSF Dynamics and ICP Elevation -- 3.10  Hydrocephalus -- 3.11  Idiopathic Intracranial Hypertension (IIH) -- 3.12  Traumatic Brain Injury -- 3.13  Intracerebral Hemorrhage -- 3.14  Subarachnoid Hemorrhage -- 3.15  Ischemic Stroke [13] -- 3.16  Conclusions.

References -- 4: Cerebral Hemodynamics -- 4.1  Introduction -- 4.1.1  Special Needs of the Brain -- 4.1.2  Unique Features of Cerebral Circulation -- 4.1.3  Determinants of Cerebral Blood Flow -- 4.2  Regulation of Cerebral Blood Flow -- 4.2.1  Regulation of Cerebral Blood Flow Can Be Divided into Four Categories (Fig. 4.4) -- 4.3  Alterations of Cerebral Blood Flow Regulation in Health and Disease -- 4.3.1  Effect of Aging -- 4.3.2  Effect of Posture -- 4.3.3  Effect of Exercise -- 4.3.4  Effect of Hypertension -- 4.3.5  Effect of Stroke -- 4.3.6  Effect of Anesthesia -- References -- Part III: Monitoring in Neurocritical Care -- 5: Intracranial Pressure Monitoring -- 5.1  Introduction -- 5.2  ICP Waveform: Physiological and Pathological Trends -- 5.3  Intracranial Pressure-Volume Relationship: Intracranial Compliance -- 5.4  ICP Interplay with Cerebral Perfusion Pressure (CPP) -- 5.5  ICP Measurement -- 5.5.1  Historical Perspective -- 5.5.2  Current Practice -- 5.5.3 Invasive ICP Monitoring -- 5.5.4 Noninvasive Techniques -- 5.6  Future Avenues for ICP Monitoring -- References -- 6: Cerebral Blood Flow Monitoring -- 6.1  Introduction -- 6.2  Arterial Supply of the Brain -- 6.3  The Physiological Aspects of Cerebral Blood Flow -- 6.3.1  Cerebral Physiology and CBF -- 6.3.2  Factors Affecting CBF [9] -- Intrinsic Factors -- Extrinsic Factors Affecting CBF -- 6.3.3  Cerebral Autoregulation (CA) -- 6.4  Cerebral Blood Flow Monitoring -- 6.4.1  General Concepts -- Fick's Principle -- The Central Volume Principle [37] -- Doppler Effect and Intensity Fluctuations [37] -- 6.4.2  Cerebral Blood Flow Monitoring Techniques -- Direct Techniques -- 6.4.3  Imaging-Based CBF Techniques -- X-Ray-Based Techniques -- MRI-Based Techniques -- Ultrasonography (USG)-Based Techniques -- 6.4.4  Optical Techniques -- 6.4.5  Nuclear Medicine-Based Techniques.

6.4.6  Monitoring Cerebral Autoregulation -- 6.4.7  Newer Advances -- Microwave-Based CBF Analysis -- Ultrasound-Tagged (UT)-NIRS -- 6.5  Conclusion -- References -- 7: Jugular Venous Oximetry -- 7.1  Introduction -- 7.2  History -- 7.3  Relevant Anatomy -- 7.4  Site of Monitoring -- 7.5  Insertion of a Jugular Bulb Catheter -- 7.6  Avoidance of Extracranial Contamination -- 7.7  Intermittent and Continuous Monitoring -- 7.8  Complications -- 7.9  The Fundamental Concepts of Jugular Venous Oximetry -- 7.10  Clinical Applications of SjVO2 -- 7.10.1  Traumatic Brain Injury -- 7.10.2  Subarachnoid Hemorrhage -- 7.10.3  Cardiac Surgeries -- 7.10.4  Neuroprognostication after Cardiac Arrest -- 7.10.5  Effect of Anesthetics on SjVO2 -- 7.11  Limitations -- 7.12  Conclusions -- References -- 8: EEG for the Intensivist: Basics -- 8.1 Introduction -- 8.2  Basics of EEG -- 8.3  Important Terminology -- 8.4  Various Patterns Seen in EEG -- 8.4.1  Normal Adult EEG -- 8.5  Pattern 3: Periodic Epileptiform Discharges (PEDs) -- 8.5.1  Periodic Lateralized Epileptiform Discharges or Lateralized Periodic Discharges -- 8.5.2  Bilateral Independent Periodic Lateralized Epileptiform Discharges -- 8.5.3  Generalized Periodic Discharges -- 8.5.4  Stimulus-Induced Periodic, Rhythmic, or Ictal Discharges (SIRPIDs) -- 8.5.5  Triphasic Waves -- 8.6  Pattern 4: Burst-Suppression Pattern (BSP) -- 8.7  Pattern 5: Electrographic Seizures -- 8.7.1  Focal Electrographic Seizures --



8.7.2  Generalized Electrographic Seizures -- 8.8  Continuous EEG -- References -- 9: Transcranial Doppler -- 9.1  Introduction -- 9.2  Physical Principle -- 9.3  Transcranial Doppler (TCD) Versus Transcranial Color-Coded Duplex Sonography (TCCD) -- 9.4  Technique of TCD -- 9.5  Spectral Waveform Analysis -- 9.6  TCD Indices -- 9.7  Assessment of Cerebral Hemodynamics by TCD -- 9.8  Clinical Uses.

9.9  Limitations of TCD -- 9.10  Summary -- References -- 10: Evoked Response Monitoring -- 10.1  Introduction -- 10.2  Applied Anatomy -- 10.3  Basics of Recording -- 10.3.1  Montages -- 10.3.2  Nearfield and Far-Field Potentials [3, 5] -- 10.3.3  Nomenclature, Amplitude, and Latency -- 10.4  Recording Technique -- 10.4.1  Upper Limb -- 10.4.2  Lower Limb -- 10.5  Interpretation -- 10.6  Prolongation of Latency -- 10.7  Changes in Amplitude -- 10.8  Absence of Waves -- 10.8.1  Upper Limb (Table 10.3) -- 10.8.2  Lower Limb (Table 10.4) -- 10.9  Factors Affecting SSEPs -- 10.10  Indications and Common Applications in Critical Care -- 10.10.1  Prognostication After Cardiac Arrest [12-18] -- 10.10.2  Prognostication After Traumatic Brain Injury [1, 19-21] -- 10.11  Other Uses -- 10.12  Multimodal Monitoring [23, 24] -- 10.13  Other Evoked Responses in Critical Care [25] -- References -- 11: Near Infrared Spectroscopy -- 11.1  Introduction -- 11.2  Factors Affecting NIRS-Based Cerebral Oximetry Readings -- 11.3  Clinical Application of NIRS-Based Cerebral Oximetry in NICU -- References -- 12: Brain Tissue Oxygenation -- 12.1  Introduction: The Physiology of Brain Oxygen -- 12.1.1  Systemic Determinants of Brain Oxygen -- 12.1.2  Arterial Oxygen Content -- 12.1.3  Cerebral Blood Flow -- 12.1.4  Capillary Oxygen Delivery -- 12.1.5  Oxygen Diffusion -- 12.2  Brain Tissue Oxygen Monitoring -- 12.2.1  Normal Values for Brain Oxygen Levels -- 12.3  Methodological Issues with Clinical Monitoring of pbtO2 -- 12.3.1  Systemic Determinants of PbtO2 -- 12.3.2  The Balance of Supply and Demand -- 12.3.3  Local Tissue Factors Influencing PbtO2 Readings -- 12.4  Brain Tissue Oxygen Monitoring in TBI -- 12.4.1  Ischemia as a Component of Secondary Brain Injury in TBI -- 12.4.2  Mechanisms of Brain Hypoxia and Dysoxia.

12.4.3  Identification of Brain Hypoxia with PbtO2 -- 12.4.4  Outcomes Associated with Low PbtO2 -- 12.4.5  Protocolized Approach to Brain Hypoxia -- 12.4.6  Randomized Trials of PbtO2-Based Management in TBI -- 12.5  Brain Tissue Oxygen Monitoring in SAH -- 12.5.1  Mechanisms of Brain Injury in SAH -- 12.6  PbtO2 Monitoring in SAH -- 12.6.1  Evidence for PbtO2 Use in SAH -- 12.7  The Future of Brain Oxygen Monitoring in Acute Brain Injury -- 12.7.1  Indices of Auto-regulation -- 12.7.2  Use of PbtO2 Monitoring in CSD -- 12.8  Conclusions -- References -- 13: Brain Microdialysis -- 13.1  Introduction -- 13.2  The Principle of Microdialysis -- 13.3  Factors Affecting Solute Recovery -- 13.3.1  Flow Rate of Perfusate -- 13.3.2  Characteristics of Semipermeable Membrane -- 13.3.3  Characteristics of Analyte -- 13.3.4  Temperature -- 13.3.5  Tissue Factors -- 13.4  Clinical Applications of Microdialysis in Brain Injury -- 13.4.1  Aneurysmal Subarachnoid Hemorrhage -- 13.4.2  Traumatic Brain Injury -- 13.4.3  Acute Ischemic Stroke -- 13.4.4  Brain Tumor -- 13.4.5  Epilepsy -- 13.5  Other Applications of Cerebral Microdialysis -- 13.6  Future Applications -- References -- 14: Neuroimaging: CT Scan and MRI -- 14.1  Introduction -- 14.2  Imaging Modalities -- 14.2.1  Computed Tomography -- 14.2.2  Magnetic Resonance Imaging -- 14.2.3  Basic Sequences of MRI -- 14.2.4  Digital Subtraction Angiography -- 14.3  Different Spectrum of Pathology -- 14.4  Summary -- References -- 15: Brain Ultrasonography -- 15.1  



Introduction -- 15.2  Principles of Brain Ultrasound -- 15.3  Clinical Applications -- 15.3.1  Midline Shift -- 15.3.2  Intraparenchymal Hemorrhage -- 15.3.3  Extra-axial Hemorrhage -- 15.3.4  Hydrocephalus -- 15.3.5  Post-surgical Applications -- 15.3.6  Limitations of Brain Ultrasound -- 15.3.7  Orbital Ultrasound -- 15.3.8  Optic Nerve Sheath Diameter.

15.3.9  Papilledema.