Intro -- Preface -- Contents -- Chapter 1: A Toxin that Remedies a Large Number of Medical Problems: How It Happened? -- References -- Chapter 2: Structure and Mechanism of Function of Botulinum Neurotoxins: How Does the Toxin Work -- Introduction -- Excessive Sweating and Drooling -- Pain -- Hyperactive Involuntary Movement Disorders (HIMD) -- References -- Chapter 3: Beyond Botox: Other Neurotoxins-What Are Similarities and Differences? -- Introduction -- Botox (Allergan Inc., Irvine California) -- Xeomin (Merz Pharmaceuticals, Frankfurt, Germany) [4] -- Dysport (Ipsen Limited, Paris France) [6] -- Jeuveau and Daxxify [7, 8] -- Myobloc (Neurobloc in Europe: WorldMed/Solstice Neurosciences, Louisville, Kentucky) [9] -- Preparation/Injection -- Non-FDA Approved Botulinum Toxins Used in Far East Asia -- Prosigne [12] -- Meditoxin/Neuronox -- Definition of Clinical Trials -- Study Class and Efficacy Evaluation -- References -- Chapter 4: Botox: A Miracle Drug for Chronic Migraine -- Introduction -- Migraine and Chronic Migraine -- Treatment of Acute Attacks -- Preventive Treatment of Migraine -- Botulinum Toxin Treatment of Migraine -- PREEMPT Studies -- Sites of Botox Injection, Recommended Dose per Site and per Session -- Injection Method -- Side Effects of Botox Therapy in Chronic Migraine -- Episodic Migraine -- Tension-Type Headaches -- Secondary Headaches -- Economic Issues -- Discussion -- References -- Chapter 5: Pain Disorders other |