1.

Record Nr.

UNINA9910861093203321

Autore

R. C. Sobti

Titolo

Handbook of Oncobiology: From Basic to Clinical Sciences / / edited by R. C. Sobti, Nirmal K. Ganguly, Rakesh Kumar

Pubbl/distr/stampa

Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024

ISBN

9789819962631

Edizione

[1st ed. 2024.]

Descrizione fisica

1 online resource

Altri autori (Persone)

GangulyNirmal K

KumarRakesh

Disciplina

571,978

616,994

Soggetti

Cancer

Pharmacology

Stem cells

Epidemiology

Nutrition

Cancer Biology

Stem Cell Biology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

includes bibliographical references and index.

Nota di contenuto

Current Concepts and Advances in Oncobiology -- History, Evolution, Milestones in Cancer Research and Treatment -- Cancer Statistics: Geographical and Racial Disparities -- A Comprehensive Overview of Various Cancer Types and Their Progression -- Strategies of Early Diagnosis of Cancers -- Advancement in Cancer Modeling System: Latest Developments and Trends in Cancer Research and Healthcare Interventions -- Point of Care Molecular Diagnostics in Cancer -- Genetics of Cancer: Past, Present and Future -- Mechanisms of Oncogenesis -- Recent Developments in Cancer Detection and Treatment -- Circadian Rhythms and Their Association with Cancer Development -- Advances in Cancer Pain Management -- Genetic Alterations and Microbial Dysbiosis Underlie Lymph Node Metastasis in Tongue Cancer -- Skin Cancer: An Overview -- Squamous Cell Carcinoma Predisposition Pathophysiology, Diagnosis, and Treatment -- Tumor Heterogeneity in Breast Cancer Progression -- Molecular



Pathways in Breast Cancer Chemoresistance -- Therapeutic Efficacy of Estrogen Related Receptor β in Breast Carcinoma -- Diagnostic-Prognostic Biomarkers and Their Clinical Implication in Breast Cancer -- Tumour Inflammatory Microenvironment in Lung Cancer: Heterogeneity and Implications -- Brain Tumors: Types, Diagnostic Biomarkers and New Therapeutic Approaches -- Current Pathophysiology, Treatment, and Future Perspective for Prostate Cancer -- Emerging Pathophysiology and Treatment Prostate Cancer: Future Perspective -- Androgen Receptor Signaling: a Central and Evolving Theme in Prostate Cancer Treatment -- Structuring Inflammasome-Epigenome – Phenotypic Axis in Gynecological Cancers.

Sommario/riassunto

This Handbook on cancer biology comprehensively reviews the current status of the oncobiology of major cancer types, cancer detection and treatment strategies, principles and processes of cancer drug development, and nanomedicine and other emerging cancer medicine applications to cancer diagnosis and treatment. The book also provides practical and implementable nutritional guidance in cancer prevention, treatment, and quality of life for cancer survivors. It discusses pharmacogenetics strategies for predicting cancer prognosis and treatment exposure, response, and toxicity. Further, it presents bioinformatics approaches for predicting anti-cancer drugs and drug combinations based on the multi-omic data, including transcriptomics, toxicogenomics, functional genomics, and biological networks. The Handbook also examines major factors and pathways that regulate cancer stem cells development and discusses potential targeted therapy for cancer stem cells. The book explores the application of the CRISPR/Cas9-based gene-editing technique in basic cancer research, diagnosis, and treatment of cancer. This Handbook is an invaluable source for oncologists, researchers, public health specialists, epidemiologists, and policy makers.