Biografia del centrosinistra, 1945-1995 / Domenico Rosati

• Record Nr.: UNISALENTO991001524919707536
• Autore: Rosati, Domenico
• Pubbl/distr/stampa: Palermo : Sellerio, 1996
• ISBN: 8838912025
• Descrizione fisica: 170 p. ; 19 cm.
• Collana: La nuova diagonale ; 12
• Disciplina: 320.945
• Soggetti: Italia Politica 1945-1995
• Lingua di pubblicazione: Italiano
• Formato: Materiale a stampa
• Livello bibliografico: Monografia

Statistics in regulatory science / / by Shein-Chung Chow

• Record Nr.: UNINA9910861081003321
• Autore: Chow Shein-Chung <1955->
• Pubbl/distr/stampa: Boca Raton : , : CRC Press, , [2018]
• ISBN: 1-000-71081-5; 1-000-71003-3; 0-429-27506-4
• Edizione: [1st ed.]
• Descrizione fisica: 1 online resource (553 pages)
• Collana: Chapman and Hall/CRC Biostatistics Series
• Disciplina: 615.19
• Soggetti: Drugs - Testing; Clinical trials - Statistical methods; Pharmacy - Research; Research - Statistical methods
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Totality-of-the-evidence -- Hypotheses testing versus confidence interval -- Endpoint selection -- Non-inferiority margin -- Missing data -- Multiplicity -- Sample size -- Reproducible research -- Extrapolation -- Consistency evaluation -- Drug products with multiple components -- Adaptive trial design -- Selection criteria in adaptive dose finding -- Generic drugs and biosimilars -- Precision and personalized medicine -- Big data analytics -- Rare disease drug development.
• Sommario/riassunto: "The proposed book will focus on practical issues in pharmaceutical/clinical research and development from both regulatory and scientific perspectives. The book will outline and clarify those issues that have been commonly misused in the subject area of regulatory science"--