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Record Nr. |
UNINA9910841739303321 |
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Titolo |
Toxicogenomics [[electronic resource] ] : a powerful tool for toxicity assessment / / editor, Saura C. Sahu |
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Pubbl/distr/stampa |
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Chichester, UK, : John Wiley & Sons, 2008 |
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ISBN |
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1-282-34264-9 |
9786612342646 |
0-470-69963-9 |
0-470-69964-7 |
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Descrizione fisica |
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1 online resource (439 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Genetic toxicology |
Genomics |
Proteomics |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Toxicogenomics; Contents; Preface; List of Contributors; Acknowledgments; SECTION 1 DESIGN, ANALYSIS AND INTERPRETATION OF TOXICOGENOMICS; 1 Mechanistic Toxicogenomics: Design and Analysis of Microarray Experiments; 2 A New Approach to Analysis and Interpretation of Toxicogenomic Gene Expression Data and its Importance in Examining Biological Responses to Low, Environmentally Relevant Doses of Toxicants; 3 Principles of Data Mining in Toxicogenomics; 4 Design Issues in Toxicogenomics: The Application of Genomic Technologies for Mechanistic and Predictive Research |
5 Sources of Variability in Toxicogenomic Assays6 Key Aspects of Toxicogenomic Data Analysis and Interpretation as a Safety Assessment Tool to Identify and Understand Drug-Induced Toxicity; SECTION 2 APPLICATIONS OF TOXICOGENOMICS; 7 Toxicogenomics as a Tool to Assess Immunotoxicity; 8 Toxicogenomics and Ecotoxicogenomics: Studying Chemical Effects and Basic Biology in Vertebrates and Invertebrates; 9 Gene Expression Profiling of Transplacental Arsenic Carcinogenesis in Mice; 10 Characterization of Estrogen-active |
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