1.

Record Nr.

UNINA9910840760503321

Titolo

Cardiovascular genetics and genomics for the cardiologist [[electronic resource] /] / edited by Victor J. Dzau, Choong-Chin Liew

Pubbl/distr/stampa

Malden, Mass., : Blackwell Futura, 2007

ISBN

1-281-06924-8

9786611069247

0-470-69197-2

0-470-76594-1

Descrizione fisica

1 online resource (330 p.)

Altri autori (Persone)

DzauVictor J

LiewChoong-Chin

Disciplina

616.1/042

616.1042

Soggetti

Cardiovascular system - Diseases - Genetic aspects

Cardiovascular system - Molecular aspects

Genomics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

The gene in the twenty-first century / Choong-Chin Liew, Victor J. Dzau -- Monogenic hypercholesterolemia / Ruth McPherson -- Hypertrophic cardiomyopathy / Ali J. Marian -- Dilated cardiomyopathy and other cardiomyopathies / Mitra Esfandiarei, Robert Yanagawa, Bruce M. McManus -- The long QT syndrome / Sabina Kupershmidt, Kamilla Kelemen, Tadashi Nakajima -- Atherosclerosis / Päivi Pajukanta, Kiat Tsong Tan, Choong-Chin Liew -- Heart failure / Markus Meyer, Peter VanBuren -- The implications of genes on the pathogenesis, diagnosis and therapeutics of hypertension / Kiat Tsong Tan, Choong-Chin Liew -- Gene therapy for cardiovascular disease: inserting new genes, regulating the expression of native genes, and correcting genetic defects / Ion S. Jovin, Frank J. Giordano -- Stem cell therapy for cardiovascular disease / Emerson C. Perin, Guilherme V. Silva -- Pharmacogenetics and personalized medicine / Julie A. Johnson, Issam Zineh -- The potential of blood-based gene profiling for disease assessment / Steve Mohr, Choon-Chin Liew.



Sommario/riassunto

Until recently, a modest knowledge of genetics was more than adequate for the daily practice of clinical cardiology, but advances in genetics and genomics are changing cardiovascular medicine in fundamental ways. The identification of the genetic basis of several forms of dyslipidemia, hypertension, diabetes, cardiomyopathies, and vascular diseases signalled the new importance of genetics in clinical medicine.  In this timely volume, Drs. Dzau and Liew - both pioneers in the area - help cardiologists understand: how cardiovascular genetics may remodel the way cardiovascular medicine