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Record Nr. |
UNINA9910784720103321 |
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Autore |
Richards David A. J |
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Titolo |
Foundations of American constitutionalism [[electronic resource] /] / David A.J. Richards |
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Pubbl/distr/stampa |
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New York, : Oxford University Press, 1989 |
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ISBN |
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1-280-52409-X |
0-19-536311-6 |
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Descrizione fisica |
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1 online resource (332 p.) |
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Disciplina |
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Soggetti |
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Constitutional history - United States |
Constitutional law - United States |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Contents; 1 Introduction; 2 The Founders' Interpretive Uses of History; 3 Political Legitimacy and Constitutional Founding; 4 Interpreting the Founders over Time; 5 Interpreting Enumerated Rights: Religious Liberty and Free Speech; 6 Interpreting Unenumerated Rights: Constitutional Privacy; 7 Interpreting Equal Protection; 8 Constitutional Decadence and Educational Responsibility; Index |
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Sommario/riassunto |
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David Richards here argues that the legal interpretation of the US constitution depends on an understanding of the liberal humanist principles which guided the Founders. |
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2. |
Record Nr. |
UNINA9910831177003321 |
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Titolo |
Growth factors and psychiatric disorders [[electronic resource]] |
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Pubbl/distr/stampa |
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Chichester, UK ; ; Hoboken, NJ, : John Wiley & Sons, 2008 |
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ISBN |
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1-281-32226-1 |
9786611322267 |
0-470-75125-8 |
0-470-75126-6 |
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Descrizione fisica |
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1 online resource (260 p.) |
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Collana |
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Novartis Foundation symposium ; ; 289 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Growth factors |
Mental illness - Genetic aspects |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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"Editors: Derek J. Chadwick (organizer) and Jamie Goode"--P. v. |
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Nota di bibliografia |
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Includes bibliographical references and indexes. |
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Nota di contenuto |
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GROWTH FACTORS AND PSYCHIATRIC DISORDERS; Contents; Chair's introduction; Phenomenology, aetiology and treatment of schizophrenia; DISCUSSION; Genetic variants in major depression; DISCUSSION; Neurotrophins in depression and antidepressant effects; DISCUSSION; Genetics of bipolar disorder: focus on BDNF Val66Met polymorphism; DISCUSSION; Mechanisms of neuregulin action; DISCUSSION; General discussion I; The fibroblast growth factor family and mood disorders; DISCUSSION; Trajectories of anatomic brain development as a phenotype; DISCUSSION |
Cell biology of BDNF and its relevance to schizophreniaDISCUSSION; Functions and mechanisms of BDNF mRNA trafficking; DISCUSSION; Hippocampal neurogenesis and depression; DISCUSSION; Neuregulins and neuronal plasticity: possible relevance in schizophrenia; DISCUSSION; Impact of genetic variant BDNF (Val66Met) on brain structure and function; DISCUSSION; General discussion II; Growth and schizophrenia: aetiology, epidemiology and epigenetics; DISCUSSION; What can we learn from the disrupted in schizophrenia 1 interactome: lessons for target identification and disease biology?; DISCUSSION |
Neurotrophins and cytokines in neuronal plasticityDISCUSSION; Closing |
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remarks; Contributor Index; Subject Index |
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Sommario/riassunto |
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The recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders may be influenced by a small number of genes with multiple actions. This is the first book to investigate the role of growth factors in these disorders, which should provide clues to the underlying biochemical mechanisms. For example, recent studies have substantiated the provocative finding that neuregulin 1 (NRG1)is a candidate gene for schizophrenia. Neuregulin and its receptors, the ErbB tyrosine kinases, are essential for development |
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