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Record Nr. |
UNINA9910830990903321 |
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Titolo |
Clinical proteomics : from diagnosis to therapy / / edited by Jennifer E. Van Eyk and Michael J. Dunn |
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Pubbl/distr/stampa |
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Weinheim, [Germany] : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2008 |
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©2008 |
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ISBN |
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1-281-94674-5 |
9786611946746 |
3-527-62215-2 |
3-527-62216-0 |
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Descrizione fisica |
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1 online resource (695 p.) |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Nota di contenuto |
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Clinical Proteomics; Contents; Editor's Overview; Acknowledgements; List of Contributors; I Technologies; 1 Preanalytical Issues in Clinical Proteomic Studies; 1.1 Introduction; 1.2 Preanalytical Factors; 1.2.1 Biological Variation; 1.2.1.1 Intrinic Influences/Factors; 1.2.1.2 Extrinsic Influences/Factors; 1.2.2 Technical Variables; 1.2.2.1 Specimen/Sample Collection Mode; 1.2.2.2 Type of Sample Container; 1.2.2.3 Sample Processing and Handling Conditions; 1.2.2.4 Sample Storage; 1.3 Summary and Concluding Remarks; 2 Protein Separation by Two-Dimensional Electrophoresis; 2.1 Introduction |
2.2 2DE: Protein Solubilization and Sample Preparation2.3 2DE: Protein Separation; 2.3.1 Focusing in the First Dimension; 2.3.2 Advances in IEF; 2.4 Improving Proteomic Coverage by Subcellular Fractionation; 2.5 Protein Detection and Image Analysis; 2.6 The Future of 2DE; 3 Protein Separation: Liquid Chromatography; 3.1 Introduction; 3.2 Liquid Chromatography; 3.2.1 HPLC Separation Principles; 3.2.2 Reversed-Phase LC (RPLC, 1DLC); 3.2.3 Affinity Chromatography; 3.2.4 Size-Exclusion Chromatography; 3.2.5 Ion-Exchange Chromatography; 3.2.6 Two-Dimensional LC |
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3.2.6.1 Chromatofocusing to Reversed Phase3.2.6.2 Ion-Exchange-Reversed-Phase Liquid Chromatography; 3.2.7 Three-Dimensional Liquid Chromatography; 3.2.8 LC Image Analysis Requirement; 3.2.9 Mass Spectrometry for LC; 3.2.9.1 MALDI-TOF MS; 3.2.9.2 ESI-MS/MS; 3.3 Conclusions; 4 HPLC in Protein Discovery; 4.1 Introduction; 4.2 LC-Based Approaches in Peptide Mass Mapping; 4.3 LC-Based Approaches in Protein Mapping; 4.4 Orthogonal 2D HPLC Separations; 4.5 Conclusion; 5 IEF Analysis of Peptides for Biomarkers Discovery; 5.1 Introduction; 5.2 Background; 5.2.1 Isoelectric Focusing |
5.2.2 Shotgun Proteomics5.2.3 Shotgun IEF; 5.3 Shotgun IEF Workflow; 5.4 Applications; 5.5 Discussion and Outlook; 6 Capillary Electrophoretic Separations for Clinical Proteomics; 6.1 Introduction; 6.2 (Single-Dimension) Capillary Electophoretic Separation; 6.3 Capillary Electrophoresis-Based Multidimensional Separations; 6.3.1 Capillary Liquid Chromatography-Capillary Electrophoresis; 6.3.2 Capillary Electrophoresis-Capillary Electrophoresis; 6.3.3 Capillary Electrophoresis-Liquid Chromatography; 6.3.3.1 Characterization of Human Saliva Proteome; 6.3.3.2 Targeted Tissue Proteomics |
6.4 Conclusions7 Quantitative Proteomics Using Nano-LC with High Accuracy Mass Spectrometry; 7.1 Introduction; 7.2 Fundamentals of a High Mass Accuracy-Based LC-MS Approach; 7.3 Nano-LC-MS for Enhanced Sensitivity and Dynamic Range Coverage; 7.4 Further Developments for Increasing Proteomic Throughput; 7.5 Obtaining More Robust Quantitative Proteomic Measurements; 7.6 Summary and Perspective; 8 Antibody Microarrays for Protein and Glycan Detection; 8.1 Introduction; 8.2 Antibody Preparation and Microarray Production; 8.3 Sandwich Assays with Fluorescence Detection |
8.4 Antibody Microarrays with Lectin Detection |
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Sommario/riassunto |
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Unparalleled in its scope and depth, this book brings together proteomic approaches in diagnosis and treatment from all clinical fields, including clinical toxicology. The result is a new discipline in molecular medicine that will revolutionize the treatment and prevention of cancer, stroke and other severe diseases.Following an overview of clinical proteomics, the authors look at the technologies available, before moving on to cancer, cardiopulmonary disease, diabetes and stroke. A whole section is devoted to toxicity and the work is rounded off with a discussion of the future of clinical |
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2. |
Record Nr. |
UNINA9910155030903321 |
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Autore |
Piatti-Farnell Lorna |
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Titolo |
Banana : a global history / / Lorna Piatti-Farnell |
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Pubbl/distr/stampa |
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London : , : Reaktion Books, , 2016 |
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London : , : Bloomsbury Publishing (US), , 2023 |
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ISBN |
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9781780235714 |
1780235712 |
9781780236063 |
1780236069 |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (175 pages) : illustrations |
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Collana |
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Disciplina |
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Soggetti |
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Bananas |
Food - History |
Food and society |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Introducing the Banana Family 1. Growing Banana: Histories, Legends and Myths 2. How to Eat Bananas 3. The Banana Trade 4. Imaginary Bananas Epilogue Recipes References Select Bibliography Websites and Associations Photo Acknowledgments Index |
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Sommario/riassunto |
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For over a century, the banana has been the world's favourite fruit. Quick and easy to eat, tasty and versatile, the banana is a staple of many diets around the globe. Its history, however, is more than simply a succession of happy family scenes and appealing exotic locations. The growth and development of the fruit we know and love today is entangled with colonial practices, capitalist enterprise, sexual politics and even horrific murders. Banana: A Global History takes us from the agricultural beginnings of the banana in New Guinea to its almost ubiquitous presence in culinary repertoires around the globe, from the United States to the Caribbean, from regions of Africa to the heart of Southeast Asia. The book gives us an insight into the life of the banana over millennia, focusing on our recent history and its cultural affair with the fruit. The global life of the banana is traced in cultural practices, advertising, commercial schemes and the unmissable icons of popular |
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culture, from nineteenth-century medical manuals to cookbooks, songs, the famous 'banana peel gag' and the well-known Miss Chiquita icon. |
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