Pseudomonas [[electronic resource] ] : model organism, pathogen, cell factory / / edited by Bernd H.A. Rehm

• Record Nr.: UNINA9910830873903321
• Pubbl/distr/stampa: Weinheim ; ; Chichester, : Wiley-VCH, 2008
• ISBN: 1-282-37224-6; 9786612372247; 3-527-62200-4; 3-527-62201-2
• Descrizione fisica: 1 online resource (426 p.)
• Altri autori (Persone): RehmBernd
• Disciplina: 579.332
• Soggetti: Pseudomonas; Pseudomonadaceae
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Pseudomonas; Contents; Preface; List of Contributors; 1 Comparative Genomics of Pseudomonas; 1.1 Introduction; 1.1.1 Other Species of Pseudomonas; 1.1.2 Obtaining Sequence Data on Pseudomonas; 1.2 Pan/Core Genome of Pseudomonas; 1.3 Phylogeny of Pseudomonas; 1.4 Blast Atlas of Pseudomonas Genomes; 1.4.1 Region 5 243 000-5 361 000; 1.4.2 Region 713 000-785 000; 1.5 Functional Categories; 1.6 Codon Usage and Expression; 1.7 Future Outlook; References; 2 Clinical Relevance of Pseudomonas aeruginosa: A Master of Adaptation and Survival Strategies; 2.1 Introduction; 2.2 CF; 2.3 Survival of P. aeruginosa by Adaptation to the Inflammatory Defense System2.4 Conductive and the Respiratory Zones of the Lungs; 2.5 Survival of P. aeruginosa by Adaptation to the Respiratory Zone of the Lungs; 2.6 Survival of P. aeruginosa by Adaptation to the Conductive Zone of the Lungs; 2.7 Survival of P. aeruginosa by Adaptation to the Antibiotic Therapy; 2.8 Evolutionary Implications of the Adaptability of P. aeruginosa; References; 3 Adherence of Pseudomonas aeruginosa; 3.1 Introduction; 3.2 What is Adherence?; 3.3 Role of Adherence in Infection; 3.4 How is Bacterial Adherence Associated with Virulence?3.5 P. ; aeruginosa Adhesins; 3.6 Surface Receptor Requirements of the Pilus Adhesin; 3.7 How Does PilA Mediate Attachment to Human Mucosal Surfaces?; 3.8 X-ray Crystallographic Structural Studies of the Pilin Structural Protein; 3.9 Structure of the Pilus Fiber; 3.10 Structure of the Receptor-Binding Domain and Location on the Pilus; 3.11 Structural Nature of the Receptor-Binding Domain; 3.12 Twitching Motility; 3.13 How Does the Pilus Attach to a Solid Surface?; 3.14 The Monkey-Bar Swing Paradox; 3.15 Molecular Basis for Receptor-binding Domain Interaction with Steel Surfaces3.16 Pili as Nanowires for Redox Reactions; 3.17 What is the Most Important Role of Adherence to P. aeruginosa; References; 4 Flagella and Pili of Pseudomonas aeruginosa; 4.1 Introduction; 4.2 Flagellum of P. aeruginosa; 4.2.1 Structure of the P. aeruginosa Flagellum; 4.2.2 Chromosomal Organization of the Flagellar Genes of P. aeruginosa; 4.2.3 Transcriptional Hierarchy of the Flagellar Genes; 4.2.4 Model Proposed for Flagellar Assembly in P. aeruginosa; 4.2.5 Environmental/Nonflagellar Regulators of Flagellar Expression4.2.6 Posttranslational Modification of Flagellin; 4.2.6.1 Flagellar Glycosylation Islands (GIs) in P. aeruginosa; 4.2.6.2 Polymorphism of the P. aeruginosa a-type GI; 4.2.7 Role of Flagella in Inflammation; 4.2.8 Role of Flagellum in Pathogenesis; 4.3 Pili of P. aeruginosa; 4.3.1 Structure of P. aeruginosa Pilus; 4.3.2 Pilus/Fimbrial Genes of P. aeruginosa; 4.3.3 Regulation of Pilus Assembly and Twitching Motility; 4.3.4 Assembly of Type IV Pili; 4.3.5 Pilin Classification; 4.3.5.1 Type IV a and b Pilins; 4.3.5.2 Group I-V Pilins
• Sommario/riassunto: Concise and up-to-date, this handy guide fills a gap in the literature by providing the essential knowledge for everyone with an interest in the topic. The result is a comprehensive overview of the most important model organism in applied microbiology that covers basic biology, pathology and biotechnological applications.