1.

Record Nr.

UNINA9910830850803321

Titolo

Superantigens : Molecular Basis for Their Role in Human Diseases / / edited by Malak Kotb, John D. Fraser

Pubbl/distr/stampa

Hoboken : , : John Wiley & Sons, Inc., , 2014

ISBN

1-68367-162-7

Descrizione fisica

1 online resource (313 pages)

Disciplina

616.0

Soggetti

Superantigens

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.

Sommario/riassunto

The first comprehensive examination of these fascinating proteins ever published. Organized into five sections and sixteen chapters, this volume provides an overview of many aspects of superantigen biology. A team of researchers covers the basic molecular mechanisms of superantigen action, their structure and function, and their role in human diseases. Additionally, it explains the clinical consequences of superantigen intoxication and the latest therapeutic interventions to combat superantigen toxicity. This volume emphasizes how newly discovered structural variations among superantigens affect their interactions with human immune cells.