1.

Record Nr.

UNINA9910830786003321

Titolo

Protein targeting with small molecules [[electronic resource] ] : chemical biology techniques and applications / / edited by Hiroyuki Osada

Pubbl/distr/stampa

Hoboken, N.J., : John Wiley & Sons, c2009

ISBN

1-282-27906-8

9786612279065

0-470-49501-4

0-470-49500-6

Descrizione fisica

1 online resource (310 p.)

Altri autori (Persone)

OsadaH <1954-> (Hiroyuki)

Disciplina

572.633

Soggetti

Protein binding

Molecular probes

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

PROTEIN TARGETING WITH SMALL MOLECULES; CONTENTS; Contributors; Preface; 1 Chemical Biology Based on Small Molecule-Protein Interaction; 2 Target Profiling of Small Molecules; 3 Novel Applications of Affinity Beads; 4 Recent Developments and Advances in Chemical Arrays; 5 Use of the Phage Display Technique to Identify the Target Protein; 6 Development of Fluorescent Probes for Small Molecules; 7 Development of Small-Molecule Ligands and Inhibitors; 8 Interaction of a Biological Response Modifier with Proteins; 9 Chemical Biology of Cell Motility Inhibitors

10 Chemical Biology of Cell Surface Oligosaccharides11 Chemical Genomics Based on Yeast Genetics; 12 Data on Small Molecules and Their Target Proteins; Index

Sommario/riassunto

Discover the link between the latest chemical biology approaches and novel drug therapies! Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications takes readers beyond the use of chemical biology in basic research, providing a highly relevant look at techniques that can address the challenges of biology and drug design and development. This indispensable bench companion features up-to-date coverage of advances in chemistry and assesses their impact



on developing new therapeutics, making it ideal for chemical biologists and medicinal chemists who a