Biomedical micro- and nanorobots in disease treatment : design, preparation, and applications / / Chun Mao and Mimi Wan

• Record Nr.: UNINA9910830782603321
• Autore: Mao Chun (Writer on microrobots)
• Pubbl/distr/stampa: Weinheim, Germany : , : WILEY-VCH GmbH, , [2023]; ©2023
• ISBN: 3-527-83977-1; 3-527-83975-5
• Descrizione fisica: 1 online resource (253 pages)
• Disciplina: 610.28
• Soggetti: Biomedical engineering; Diseases - Treatment; Microrobots
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Cover -- Title Page -- Copyright -- Contents -- Preface -- Chapter 1 Introduction -- 1.1 Origin of Biomedical Micro‐ and Nanorobots -- 1.2 A Long Journey -- 1.3 Moment of Glory -- 1.4 Three Laws -- 1.5 Main Contents of this Book -- References -- Chapter 2 Definition and Classification -- 2.1 Definition -- 2.2 Classification -- References -- Chapter 3 Design and Preparation -- 3.1 Substrate Selection -- 3.1.1 Metal Materials -- 3.1.2 Inorganic Materials -- 3.1.3 Organic Materials -- 3.1.4 Natural Materials -- 3.1.5 Hybrid Materials -- 3.2 Driving System -- 3.2.1 Driving System Based on Biological Components -- 3.2.2 Driving System Based on External Fields -- 3.2.3 Driving System Based on Chemical Reactions -- References -- Chapter 4 Characterization -- 4.1 Characterization of Motion -- 4.1.1 In Aqueous Environment -- 4.1.2 In Complex Environments In Vitro -- 4.2 In Vivo Tracking Technologies -- 4.2.1 Fluorescence Imaging Technology -- 4.2.2 MRI Technology -- 4.2.3 Radionuclide Imaging Technology -- 4.2.4 Ultrasonic Imaging Technology -- 4.2.5 Other Imaging Methods -- References -- Chapter 5 Biosafety -- 5.1 Biosafety of Micro‐ and Nanorobot Substrate -- 5.1.1 Material Composition -- 5.1.2 Micro‐ and Nanoscale Influence -- 5.1.3 Interaction with Physiological Environment ; In Vivo -- 5.1.4 Ultimate Destiny -- 5.1.5 Genotoxicity -- 5.1.6 Research Method of Biosafety -- 5.2 Biosafety of Driving System of Micro‐ and Nanorobots -- 5.2.1 Biological Micro‐ and Nanorobots -- 5.2.2 Physical Field‐Driven Micro‐ and Nanorobots -- 5.2.3 Chemical Reaction‐Driven Micro‐ and Nanorobots -- 5.3 Biosafety of Autonomous Motion Behavior of Micro‐ and Nanorobots -- 5.4 Biosafety Evaluation Methods for Micro‐ and Nanorobots -- References -- Chapter 6 Autonomous Motion Behavior -- 6.1 Autonomous Motion Mechanism.; 6.1.1 Motion Mechanism of Biological Micro‐ and Nanorobots -- 6.1.1.1 Bacteria -- 6.1.1.2 Sperm -- 6.1.1.3 Immune Cells -- 6.1.2 Motion Mechanism of Physical Field‐Driven Micro‐ and Nanorobots -- 6.1.2.1 Magnetic Field‐Driving Mode -- 6.1.2.2 Photic Driving Mode -- 6.1.2.3 Ultrasonic Field‐Driving Mode -- 6.1.3 Motion Mechanism of Chemical Reaction‐Driven Micro‐ and Nanorobots -- 6.1.3.1 Self‐Electrophoresis Mode -- 6.1.3.2 Self‐Diffusiophoresis Mode -- 6.1.3.3 Bubble Mode -- 6.2 Trend Behavior Mechanism -- 6.2.1 Magnetotactic System -- 6.2.2 Phototactic System -- 6.2.3 Chemotaxis System -- 6.3 Motion Control -- 6.3.1 Speed Control Mode -- 6.3.2 Direction Control Mode -- 6.3.3 Control of Start and Stop -- References -- Chapter 7 Functions -- 7.1 Moving in Complex Physiological Environment -- 7.2 Loading Power Source, Drug, or Imaging Agent -- 7.3 Targeting Specific Cells or Physiological Tissues -- 7.4 Promoting Cell Uptake and Improving Tissue Permeability -- 7.5 Imaging Capability -- 7.6 Information Interaction and Intelligent Decision -- 7.7 Diagnosis and Treatment of Disease -- References -- Chapter 8 For Cardiovascular Disease Treatment -- 8.1 Thrombus -- 8.2 Atherosclerosis -- 8.3 Cerebral Apoplexy -- References -- Chapter 9 For Cancer Treatment -- 9.1 Cancer Diagnosis -- 9.2 Targeting and Delivery -- 9.3 Treatment of Different Cancer Species -- 9.4 Treatment Mechanism -- 9.4.1 Chemotherapy -- 9.4.2 Metabolic Therapy -- 9.4.3 Gas Therapy -- 9.4.4 Optical Therapy -- 9.4.5 Biotherapy -- 9.4.6 Immunotherapy -- 9.4.7 Multimodal Combined Therapy -- 9.5 Theranostics -- References -- Chapter 10 For Other Diseases' Treatment -- 10.1 Ophthalmic Diseases -- 10.2 Orthopedic Diseases -- 10.3 Gastrointestinal Diseases -- 10.4 Neurological Diseases -- 10.5 Bacterial Infection -- 10.6 Blood Heavy Metal Poisoning -- References.; Chapter 11 Future Development Trend -- 11.1 Biosafety of Micro‐ and Nanorobots -- 11.2 New Materials and Technologies of Micro‐ and Nanorobots -- 11.3 Intelligent Micro‐ and Nanorobots -- 11.4 New Treatment Mode -- 11.5 New Detection Technology for Micro‐ and Nanorobots -- 11.6 Outlook and Future Challenges -- References -- Postscript -- Glossary -- Index -- EULA.