Carbohydrate recognition in cellular function [[electronic resource]]

• Record Nr.: UNINA9910830699103321
• Pubbl/distr/stampa: Chichester [England] ; ; New York, : Wiley, 1989
• ISBN: 1-282-34761-6; 9786612347610; 0-470-51382-9; 0-470-51383-7
• Descrizione fisica: 1 online resource (306 p.)
• Collana: Ciba Foundation symposium ; ; 145
• Altri autori (Persone): BockGregory; HarnettSara
• Disciplina: 574.87; 574.876; 599.019248
• Soggetti: Cell receptors; Carbohydrates; Cellular recognition
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: "Symposium on Carbohydrate Recognition in Cellular Function, held at the Ciba Foundation, London, 15-17 November 1988"--P v.; "Editors: Gregory Bock (organizer) and Sara Harnett"--p v.; "A Wiley-Interscience publication."
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: CARBOHYDRATE RECOGNITION IN CELLULAR FUNCTION; Contents; Introduction; Oligosaccharide-protein interactions: a three-dimensional view; Multifunctional glycoprotein receptors for insulin and the insulin-like growth factors; Multiple subfamilies of carbohydrate recognition domains in animal lectins; Glycoprotein oligosaccharides as recognition structures; Binding modes of mammalian hepatic Gal/GalNAc receptors; General discussion I : Two human lysosomal membrane glycoproteins; Nucleoplasmic and cytoplasmic glycoproteins; Bioactive ganglioside-mediated carbohydrate recognition in coupling with ecto-protein phosphorylationRole of carbohydrates in receptor-mediated fertilization in mammals; Families of neural adhesion molecules; Structural and biological properties of the carbohydrate ; units of nervous tissue glycoproteins; Carbohydrate recognition in neuronal development: structure and expression of surface oligosaccharides and B-galactoside-binding lectins; General discussion II : Expression of developmentally regulated carbohydrates; Function and pathology of the sugar chains of human immunoglobulin G; The role of oligosaccharides in modifying protein functionLeukosialin, a major sialoglycoprotein defining leucocyte differentiation; Final general discussion : The diversity of N-linked oligosaccharides on human immunodeficiency virus; Chairman's summing-up; Index of contributors; Subject index
• Sommario/riassunto: Contributors to this volume explore the role of carbohydrates in communication between cells of multicellular organisms. Topics covered include the thermodynamics and spatial restrictions of oligosaccharide-protein interactions, the role of carbohydrates in recognition and as components of cell adhesion molecules, and abnormal glycosylation in several disease states.