1.

Record Nr.

UNINA9910830581003321

Titolo

Cellular Signaling and Innate Immune Responses to RNA Virus Infections / / edited by Allan R. Brasier, Adolfo García-Sastre, Stanley M. Lemon

Pubbl/distr/stampa

Hoboken : , : John Wiley & Sons, Inc., , 2014

ISBN

1-68367-141-4

Descrizione fisica

1 online resource (436 pages) : illustrations

Disciplina

571.7

Soggetti

Cellular signal transduction

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.

Sommario/riassunto

Divided into two major sections, this volume synthesizes recent findings in this fast-moving field while also reviewing accepted knowledge. The first part focuses on the antiviral signaling pathways in the host, including specific pattern recognition receptors (PRRs) and how these cellular alarms signal the innate immune response. The second section examines the ways in which specific major RNA virus families interact with, activate, and elude these signaling pathways and responses.