Applied biocatalysis : from fundamental science to industrial applications / / edited by Lutz Hilterhaus [and three others]

• Record Nr.: UNINA9910830572203321
• Pubbl/distr/stampa: Weinheim, Germany : , : Wiley-VCH Verlag GmbH & Co. KGaA, , 2016; ©2016
• ISBN: 3-527-67714-3; 3-527-67713-5; 3-527-67712-7
• Descrizione fisica: 1 online resource (464 p.)
• Disciplina: 660.634
• Soggetti: Enzymes - Biotechnology; Biocatalysis; Enzymes - Industrial applications
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: Cover; Title Page; Copyright; Contents; List of Contributors; Preface; Part A Molecular Biology, Enzyme Screening and Bioinformatics; Part B Biocatalytic Synthesis; Part C Reaction and Process Engineering; Index; EULA; Chapter 1 Engineering Lipases with an Expanded Genetic Code; Chapter 2 Screening of Enzymes: Novel Screening Technologies to Exploit Noncultivated Microbes for Biotechnology; Chapter 3 Robust Biocatalysts - Routes to New Diversity; Chapter 4 Application of High-Throughput Screening in Biocatalysis; Chapter 5 Supporting Biocatalysis Research with Structural Bioinformatics; Chapter 6 Engineering Proteases for Industrial ApplicationsChapter 7 Biocatalytic Synthesis of Natural Products by O-Methyltransferases; Chapter 8 Biocatalytic Phosphorylation of Metabolites; Chapter 9 Flavonoid Biotechnology - New Ways to High-Added-Value Compounds; Chapter 10 Transaminases - A Biosynthetic Route for Chiral Amines; Chapter 11 Biocatalytic Processes for the Synthesis of Chiral Alcohols; Chapter 12 Inorganic Adsorbents in Enzymatic Processes; Chapter 13 Industrial Application of Membrane ; Chromatography for the Purification of Enzymes; Chapter 14 Fermentation of Lactic Acid Bacteria: State of the Art and New PerspectivesChapter 15 The Bubble Column Reactor: A Novel Reactor Type for Cosmetic Esters; Chapter 16 Pharmaceutical Intermediates by Biocatalysis: From Fundamental Science to Industrial Applications; Chapter 17 Biocatalysis toward New Biobased Building Blocks for Polymeric Materials; 1.1 Introduction; 1.2 Enzyme Activity of Lipases from Different Sources and Engineering Approaches; 1.3 Noncanonical Amino Acids in Lipase Design and Engineering; 1.4 Case Study: Manipulating Proline, Phenylalanine, and Methionine Residues in Lipase1.5 ""Unnatural"" Lipases Are Able to Catalyze Reactions under Different Hostile Environments; 1.6 Lipase Engineering via Bioorthogonal Chemistries: Activity and Immobilization; 1.7 Conclusions and Perspectives; References; 2.1 Introduction; 2.2 Sequence- versus Function-Based Metagenomic Approach to Find Novel Biocatalysts; 2.3 Alternative Hosts, Metatranscriptomics, and Metaproteomics; 2.4 Future Perspectives; References; 3.1 Introduction; 3.2 Metagenomics to Retrieve New Genes from Extremophilic Microorganisms3.3 Microbial Expression Hosts for the Production of Extremozymes; 3.4 Molecular Biology Approaches for Enzyme Improvement; 3.5 Conclusions and Future Perspectives; References; 4.1 Introduction; 4.2 Discussions; 4.3 Summary; References; 5.1 Introduction; 5.2 Computational Tools to Assist Biocatalysis Research; 5.3 From Active Site Analysis to Protein Stability Considerations; 5.4 Applying DoGSiteScorer and HYDE to Biocatalytical Questions; 5.5 Conclusion and Future Directions; Acknowledgments; References; 6.1 Proteases in Industry