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1. |
Record Nr. |
UNINA9910454755103321 |
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Autore |
Plantin Guillaume |
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Titolo |
When insurers go bust [[electronic resource] ] : an economic analysis of the role and design of prudential regulation / / Guillaume Plantin, Jean-Charles Rochet |
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Pubbl/distr/stampa |
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Princeton, : Princeton University Press, 2007 |
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ISBN |
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1-282-12973-2 |
9786612129735 |
1-4008-2777-9 |
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Edizione |
[Course Book] |
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Descrizione fisica |
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1 online resource (112 p.) |
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Classificazione |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Insurance - State supervision |
Insurance law - Economic aspects |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references (p. [99]-101). |
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Nota di contenuto |
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Four recent cases of financially distressed insurers -- The state of the art in prudential regulation -- Inversion of the production cycle and capital structure of insurance companies -- Absence of a tough claimholder in the financial structure of insurance companies and incomplete contracts -- How to organize the regulation of insurance companies -- The role of reinsurance -- How does insurance regulation fit within other financial regulations? -- Conclusion : Prudential regulation as a substitute for corporate governance. |
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Sommario/riassunto |
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In the 1990's, large insurance companies failed in virtually every major market, prompting a fierce and ongoing debate about how to better protect policyholders. Drawing lessons from the failures of four insurance companies, When Insurers Go Bust dramatically advances this debate by arguing that the current approach to insurance regulation should be replaced with mechanisms that replicate the governance of non-financial firms. Rather than immediately addressing the minutiae of supervision, Guillaume Plantin and Jean-Charles Rochet first identify a fundamental economic rationale for supervising the solvency of insurance companies: policyholders are the "bankers" of insurance |
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companies. But because policyholders are too dispersed to effectively monitor insurers, it might be efficient to delegate monitoring to an institution--a prudential authority. Applying recent developments in corporate finance theory and the economic theory of organizations, the authors describe in practical terms how such authorities could be created and given the incentives to behave exactly like bankers behave toward borrowers, as "tough" claimholders. |
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2. |
Record Nr. |
UNINA9910830531903321 |
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Titolo |
Biology of IGF-1 [[electronic resource] ] : its interaction with insulin in health and malignant states / / [edited by Gregory Bock, Jamie Goode] |
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Pubbl/distr/stampa |
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The Atrium, Southern Gate, Chichester, UK ; ; Hoboken, NJ, : John Wiley & Sons, c2004 |
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ISBN |
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1-280-27251-1 |
9786610272518 |
0-470-66753-2 |
0-470-86997-6 |
0-470-86999-2 |
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Descrizione fisica |
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1 online resource (294 p.) |
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Collana |
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Novartis Foundation symposium ; ; 262 |
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Classificazione |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Somatomedin - Physiological effect |
Somatomedin - Pathophysiology |
Carcinogenesis |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and indexes. |
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Nota di contenuto |
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Circulating IGF-I and its role in cancer: lessons from the IGF-1 gene-deletion (LID) mouse -- Physiology of the IGF system -- Molecular basis of insulin action -- IGF-1 and insulin as growth hormones -- Insulin-like growth factors and neoplasia -- Loss of IGF2 imprinting: mechanisms and consequences -- Insulin and IGF-1 receptor |
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trafficking and signalling -- The mTOR/S6K signalling pathway: the role of the TSC1/2 tumour suppressor complex and the proto-oncogene Rheb -- Structural biology of insulin and IGF-1 receptors -- Genetic blockade of the insulin-like growth factor-I receptor for human malignancy -- IGF-1 and prostate cancer -- IGF-1 and breast cancer -- IGFBPs and cancer -- The IGF receptor as anticancer treatment target -- Nutrition, insulin, IGF-1 metabolism and cancer risk: a summary of epidemiological evidence. |
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Sommario/riassunto |
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An invaluable book containing a series of interdisciplinary discussions between clinical and basic scientists. Biology of IGF-1: Its interaction with insulin and health and malignant states focuses on key issues such as:the definition of danger zonesthe development of methods for early recognition of malignant states linked to IGF-1 and/or insulinpossible approaches to preventative interventionthe relevance in this field of research to the development of novel therapeutic approaches to treating certain cancers. |
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