A comprehensive introduction to differential geometry

• Record Nr.: UNINA990000852390403321
• Autore: Spivak, Michael
• Pubbl/distr/stampa: s.l. : Publish or Perich Inc. Berke ley, 1979
• Edizione: [2.ed.]
• Locazione: FINBN
• Collocazione: 000085239000001
• Lingua di pubblicazione: Italiano
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Vol. IV

G protein-coupled receptors [[electronic resource] ] : molecular pharmacology from academic concept to pharmaceutical research / / Georges Vauquelin, Bengt von Mentzer

• Record Nr.: UNINA9910830463003321
• Autore: Vauquelin Georges
• Pubbl/distr/stampa: Chichester, England ; ; Hoboken, NJ, : John Wiley & Sons, c2007
• ISBN: 1-282-34870-1; 9786612348709; 0-470-51665-8; 0-470-51664-X
• Descrizione fisica: 1 online resource (266 p.)
• Altri autori (Persone): MentzerBengt von
• Disciplina: 615.19
• Soggetti: G proteins - Receptors; Molecular pharmacology
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references (p. [235]-243) and index.
• Nota di contenuto: Chemical messengers and the cell membrane -- Radioligand binding studies -- Functional studies -- G protein-coupled receptors -- Concluding remarks.
• Sommario/riassunto: G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging from cell-cell communication processes to physiological responses. They play an important role in a variety of diseases from cancer and diabetes, to neurodegenerative, inflammatory and respiratory disorders. GPCRs are therefore of utmost interest in drug development: over half of all prescription drugs currently on the market act by targeting these receptors directly or indirectly. G Protein-coupled Receptors: Molecular Pharmacology provi