1.

Record Nr.

UNISA996390216603316

Autore

North Dudley North, Baron, <1602-1677.>

Titolo

Some notes concerning the life of Edward Lord North, Baron of Kirtling, 1658 [[electronic resource] /] / by Sir Dudley North Lord North

Pubbl/distr/stampa

[London, : s.n., 1682]

Descrizione fisica

[7], 42 p

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Inter bonos non obsolescit beneficiorum memoria."

This item is found at reel 544:ll (bound with Wing N1284B) and at reel 818:15 as Wing N1282 (number cancelled in Wing 2nd. ed.), and at reel 1730:27 as Wing N1286A.

Reproduction of original in Huntington Library.

Sommario/riassunto

eebo-0113



2.

Record Nr.

UNINA9910830360303321

Titolo

Molecular biology in cellular pathology [[electronic resource] /] / edited by John Crocker, Paul G. Murray

Pubbl/distr/stampa

Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, c2003

ISBN

1-280-27200-7

9786610272006

0-470-29924-X

0-470-86498-2

0-470-86794-9

Descrizione fisica

1 online resource (403 p.)

Altri autori (Persone)

CrockerJ

MurrayPaul, Ph. D.

Disciplina

611.018

611.0181

Soggetti

Pathology, Molecular

Pathology, Cellular

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Completed rev. & updated version of: Molecular biology in histopathology, 1994.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Molecular Biology in Cellular Pathology; Contents; Preface; Preface to Molecular Biology in Histopathology; List of Contributors; 1 Blotting Techniques: Methodology and Applications; 1.1 Introduction; 1.2 Blotting techniques; 1.3 References; 2 In-situ Hybridisation in Histopathology; 2.1 Introduction; 2.2 Experimental conditions; 2.3 Probes and labels; 2.4 Controls and pitfalls; 2.5 Double-labelling; 2.6 Increasing the sensitivity of ISH; 2.7 What we do in our laboratories; 2.8 Applications of ISH: examples; 2.9 Perspective; 2.10 References; 3 DNA Flow Cytometry; 3.1 Introduction

3.2 Definitions and terms3.3 Dye used for DNA analysis; 3.4 Sample preparation for DNA analysis; 3.5 Analysis of the DNA histogram; 3.6 Quality control; 3.7 Computer analysis of the DNA histogram; 3.8 Multiparametric measurement; 3.9 Acknowledgements; 3.10 References; 4 Interphase Cytogenetics; 4.1 Introduction; 4.2 Interphase



cytogenetics; 4.3 Applications; 4.4 Conclusion; 4.5 References; 5 Oncogenes; 5.1 Introduction; 5.2 Identification of the oncogenes; 5.3 Functions of the proto-oncogenes; 5.4 Mechanism of oncogene activation; 5.5 Oncogenes in colorectal cancer

5.6 Oncogenes in breast cancer5.7 Oncogenes in lung cancer; 5.8 Oncogenes in haematological malignancies; 5.9 Other cancers; 5.10 Conclusion; 5.11 References; 6 Molecular and Immunological Aspects of Cell Proliferation; 6.1 The cell cycle and its importance in clinical pathology; 6.2 Molecular control of the cell cycle; 6.3 Cell cycle control; 6.4 The cell cycle and cancer; 6.5 Immunocytochemical markers of proliferating cells; 6.6 References; 6.7 Further Reading; 7 Interphase Nucleolar Organiser Regions in Tumour Pathology; 7.1 Introduction; 7.2 The AgNORs; 7.3 NOR silver-staining

7.4 Quantitative AgNOR analysis7.5 AgNORs as a parameter of the level of cell proliferation; 7.6 Application of the AgNOR technique to tumour pathology; 7.7 What future for AgNORs in tumour pathology?; 7.8 References; 8 Apoptosis and Cell Senescence; 8.1 Introduction; 8.2 Apoptosis; 8.3 Cell senescence; 8.4 Summary; 8.5 References; 9 The Polymerase Chain Reaction; 9.1 Introduction; 9.2 Principles; 9.3 Analysis of products; 9.4 RT-PCR; 9.5 Quantitative PCR; 9.6 DNA and RNA extraction; 9.7 Correlation of the PCR with morphology; 9.8 Problems; 9.9 Applications; 9.10 Diagnostic applications

9.11 Infectious diseases9.12 Identity; 9.13 The future; 9.14 References; 9.15 Online information; 10 Laser Capture Microdissection: Techniques and Applications in the Molecular Analysis of the Cancer Cell; 10.1 Introduction; 10.2 The principle of LCM; 10.3 Technical considerations; 10.4 Advantages and disadvantages of LCM; 10.5 Applications of LCM; 10.6 Future perspectives; 10.7 Acknowledgements; 10.8 References; 11 The In-situ Polymerase Chain Reaction; 11.1 Introduction; 11.2 Overview of the methodology; 11.3 In-cell PCR technologies; 11.4 In-cell amplification of DNA

11.5 Detection of amplicons

Sommario/riassunto

The latest edition of this highly successful text, covers the major advances in the methods used in cellular and molecular pathology. In recent years, knowledge of the molecular organization of the cell has led to the development of powerful new techniques that bring greater accuracy and objectives to the diagnosis, prognosis and management of many diseases and to the study of pathological states. This book describes the latest molecular techniques available for the analysis of diseases. In particular it includes new techniques using fluorescent dyes, DNA microarrays, protein chemistry, and ma