1.

Record Nr.

UNINA9910830341803321

Titolo

The genetics and biology of sex determination

Pubbl/distr/stampa

[Place of publication not identified], : John Wiley, 2002

ISBN

9786610556120

0-470-86873-2

Descrizione fisica

1 online resource (275 pages)

Disciplina

571.882

Soggetti

Genetic sex determination

Sex Determination Processes

Physiology

Human Anatomy & Physiology

Health & Biological Sciences

Congress.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Sommario/riassunto

Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be explored at the cellular and molecular levels. A major landmark was the discovery in 1990 of the SRY gene and the subsequent demonstration of its key role in triggering male sex determination in transgenic mice. This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination, consideration of the biology of sexual development and discussion of the evolution of sex-determining mechanisms. By bringing together an international and interdisciplinary group of experts who study many different aspects of the problem, the book highlights much new and exciting work in this area and serves to identify and stimulate promising new research directions.