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Record Nr. |
UNINA9910830339303321 |
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Autore |
Lednicer Daniel <1929-> |
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Titolo |
Strategies for organic drug synthesis and design [[electronic resource] /] / Daniel Lednicer |
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Pubbl/distr/stampa |
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Hoboken, N.J., : John Wiley & Sons, c2009 |
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ISBN |
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1-282-03106-6 |
9786612031069 |
0-470-39961-9 |
0-470-39959-7 |
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Edizione |
[2nd ed.] |
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Descrizione fisica |
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1 online resource (702 p.) |
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Disciplina |
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Soggetti |
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Pharmaceutical chemistry |
Drugs - Synthesis |
Drugs - Design |
Organic compounds - Synthesis |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and indexes. |
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Nota di contenuto |
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Prostaglandins, peptidomimetic compounds, and retinoids -- Drugs based on a substituted benzene ring -- Indenes, naphthalenes, and other polycyclic aromatic compounds -- Steroids; pt. 1 : estranes, gonanes, and androstanes -- Steroids; pt. 2 : compounds related to progesterone, cortisone, and cholesterol -- Nonsteroidal sex hormones and their antagonists -- Opioid anagesics -- Drugs based on five-membered heterocycles -- Drugs based on six-membered heterocycles -- Five-membered heterocycles fused to a benzene ring -- Six-membered heterocycles fused to a benzene ring -- Seven-membered heterocycles fused to benzene -- Heterocyles fused to two aromatic rings -- Beta lactam antibiotics -- Heterocycles fused to other heterocyclic rings. |
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Sommario/riassunto |
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This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and |
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new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. A |
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