Microbial bioreactors for industrial molecules / / edited by Sudhir P. Singh and Santosh Kumar Upadhyay

• Record Nr.: UNINA9910830335703321
• Pubbl/distr/stampa: Hoboken, NJ : , : Wiley, , [2023]; ©2023
• ISBN: 1-119-87409-2; 1-119-87407-6
• Descrizione fisica: 1 online resource (515 pages)
• Disciplina: 170
• Soggetti: Bioreactors
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Cover -- Title Page -- Copyright Page -- Contents -- List of Contributors -- Chapter 1 Microbial Bioreactors: An Introduction -- 1.1 Microbial Bioresources -- 1.2 Microbial Bioresources for the Production of Enzymes -- 1.3 Microbial Bioresources for Therapeutic Application -- 1.4 Microbial Bioresources for Biogenesis -- 1.5 Microbial Fermentation -- 1.6 Microbial Biodegradation -- 1.7 Microbioresources for High-Value Metabolites -- Acknowledgments -- References -- Chapter 2 Microbial Bioresource for the Production of Marine Enzymes -- 2.1 Introduction -- 2.2 Prokaryotes -- 2.2.1 Amylases -- 2.2.2 Proteases -- 2.2.3 Bactericide -- 2.2.4 l-Asparaginase -- 2.2.5 Carbohydrases -- 2.3 Marine Archaea -- 2.4 Eukaryotes -- 2.4.1 Yeasts -- 2.4.2 Enzymes from Marine-Derived Fungi -- References -- Chapter 3 Lactic Acid Production Using Microbial Bioreactors -- 3.1 Introduction -- 3.2 Microbial Lactic Acid Producers -- 3.2.1 Bacteria -- 3.2.2 Fungi and Yeast -- 3.2.3 Microalgae -- 3.3 Alternative Substrates for Lactic Acid Production -- 3.4 Fermentation Process Parameters -- 3.5 Mode Improvement of Lactic Acid and Reactor Configuration -- 3.6 Challenges -- 3.7 Conclusions -- Acknowledgments -- References -- Chapter 4 Advancement in the Research and Development of Synbiotic Products -- 4.1 Introduction -- 4.2 Probiotics, Prebiotics, and Synbiotics -- 4.2.1 Probiotics -- 4.2.2 Requirements and Selection Criteria for Probiotic Strains -- 4.3 Prebiotics -- 4.3.1 Requirements ; and Selection Criteria for Prebiotic Strains -- 4.4 Synbiotics -- 4.4.1 Synbiotic Selection Criteria -- 4.4.2 Mechanism of Action of Synbiotics -- 4.5 Health Benefits from Synbiotics -- 4.6 Bioreactor Design for Synbiotic Production -- 4.7 Microencapsulation and Nanotechnology to Ensure Their Viability -- 4.8 Nanoparticles.; 4.9 Applications in Various Fields such as Dermatological Diseases, Animal Feed, and Functional Foods -- 4.9.1 Dermatological Diseases -- 4.9.2 Functional Foods -- 4.9.3 Animal Feed -- 4.10 Conclusions -- References -- Chapter 5 Microbial Asparaginase and Its Bioprocessing Significance -- 5.1 Introduction -- 5.2 Classification of l-Asparaginase -- 5.3 Bioprocessing -- 5.3.1 Sources of microbial l-Asparaginase -- 5.3.2 Upstream Bioprocessing -- 5.3.3 Downstream Bioprocessing -- 5.4 Scaled Up to Bioreactor -- 5.5 Characterization of l-Asparaginase -- 5.6 Applications of l-Asparaginase -- 5.6.1 Pharmaceutical Industry -- 5.7 Conclusions -- 5.6.2 Food Industry -- References -- Chapter 6 Bioreactor-Scale Strategy for Pectinase Production -- 6.1 Introduction -- 6.2 Pectinase Classification and Origin Sources -- 6.2.1 Pectinases -- 6.2.2 Origin Source of Production of Microbial Pectinase -- 6.3 Substrates Used for Pectinase Production -- 6.4 Fermentation Strategies -- 6.4.1 Solid-State Fermentation -- 6.4.2 Submerged Fermentation -- 6.5 Bioreactor-Scale Strategies -- 6.6 Conclusions -- References -- Chapter 7 Microbes as a Bio-Factory for Polyhydroxyalkanoate Biopolymer Production -- 7.1 Introduction -- 7.2 Microbial Polyhydroxyalkanoates as a Novel Alternative to Substitute Petroleum-Derived Plastics -- 7.3 Microbial PHAs Classification, Synthesis, and Producing Microorganisms -- 7.3.1 PHAs Classification -- 7.3.2 Biosynthetic Pathways for PHAs Production -- 7.3.3 PHAs Producing Strains -- 7.3.4 Bacteria as the Main Species for the PHA Production -- 7.3.5 Algae as a Feasible Alternative for PHA Production -- 7.4 Trends and Challenges in the PHAs Synthesis Process -- 7.4.1 Upstream Processing Trends and Challenges -- 7.4.2 Downstream Processing, Trends and Challenges -- 7.5 Process Economics and Perspectives Toward Industrial Implementation.; 7.6 Concluding Remarks -- References -- Chapter 8 Microbial Production of Critical Enzymes of Lignolytic Functions -- 8.1 Introduction -- 8.2 Sources of Lignolytic Enzymes -- 8.2.1 Plants -- 8.2.2 Insects -- 8.2.3 Bacteria -- 8.2.4 Fungi -- 8.2.5 Actinomycetes -- 8.2.6 Extremophiles -- 8.3 Lignolytic Enzymes -- 8.3.1 Lignin Peroxidase (EC 1.11.1.14) -- 8.3.2 Manganese Peroxidase (EC 1.11.1.13) -- 8.3.3 Versatile Peroxidase (EC 1.11.1.16) -- 8.3.4 Dye Decolorizing Peroxidases (DyPs) (EC 1.11.1.19) -- 8.3.5 Laccases (EC 1.10.3.2) -- 8.3.6 Feruloyl Esterase (EC.3.1.1.73) -- 8.3.7 Aryl Alcohol Oxidase (EC 1.1.3.7) -- 8.3.8 Pyranose-2-Oxidase (EC 1.1.3.10) -- 8.3.9 Vanillyl Alcohol Oxidase (EC 1.1.3.38) -- 8.3.10 Quinone Reductase (EC 1.6.5.5) -- 8.4 Microbial Production of Lignolytic Enzymes -- 8.5 Mechanism of Action of Lignolytic Enzymes -- 8.6 Conclusions -- Acknowledgments -- References -- Chapter 9 Microbial Bioreactors for Biofuels -- 9.1 Introduction -- 9.2 General Classification of Bioreactor -- 9.3 Liquid-Phase Bioreactor -- 9.3.1 Cell-Free -- 9.3.2 Immobilized Cell -- 9.4 Reactors for Solid-State Cultures -- 9.5 Bioreactor Operation Mode -- 9.6 Biofuels -- 9.6.1 Bioethanol -- 9.6.2 Biodiesel -- 9.6.3 Butanol -- 9.6.4 Biogas and Methane -- 9.6.5 Hydrogen -- 9.6.6 Biohythane -- 9.7 Considerations and Future Perspectives -- References -- Chapter 10 Potential Microbial Bioresources for Functional Sugar Molecules -- 10.1 Introduction -- 10.2 d-Allulose -- 10.3 d-Tagatose -- 10.4 Trehalose -- 10.5 Turanose -- 10.6 Trehalulose -- 10.7 d-Allose -- 10.8 d-Talose -- 10.9 Conclusions -- Acknowledgment -- References -- ; Chapter 11 Microbial Production of Bioactive Peptides -- 11.1 Introduction -- 11.2 Microbial Production of Peptides with Antioxidant Activity -- 11.3 Microbial Production of Peptides with Antimicrobial Activity.; 11.4 Microbial Production of Peptides with Antihypertensive Activity -- 11.5 Microbial Production of Peptides with Antidiabetic Activity -- 11.6 Microbial Production of Peptides with Immunomodulatory Activities -- 11.7 Microbial Production of Peptides with Antitumoral Activity -- 11.8 Microbial Production of Peptides with Opioid Activity -- 11.9 Microbial Production of Peptides with Antithrombotic Activity -- 11.10 Production of Recombinant Peptides in Microbial Expression Systems -- 11.11 Purification and Identification of Microbial Bioactive Peptides -- 11.12 Conclusions and Perspectives -- References -- Chapter 12 Trends in Microbial Sources of Oils, Fats, and Fatty Acids for Industrial Use -- 12.1 Introduction -- 12.2 Microbial Sources -- 12.2.1 Microalgal Sources -- 12.2.2 Bacterial Sources -- 12.2.3 Fungal and Yeast Sources -- 12.3 Application in Food and Health -- 12.4 Opportunities and Prospective Future -- 12.5 Conclusion -- References -- Chapter 13 Microbial Bioreactors for Secondary Metabolite Production -- 13.1 Introduction -- 13.2 Design of Bioreactors -- 13.3 Types of Bioreactors for Secondary Metabolite Production -- 13.3.1 Stirred Tank Bioreactor (STB) -- 13.3.2 Bubble Column -- 13.3.3 Air-Lift -- 13.3.4 Biofilm Bioreactor -- 13.3.5 Solid-State Fermentation (SSF) Bioreactors -- 13.3.6 Tray Bioreactor -- 13.3.7 Packed Bed Bioreactor -- 13.3.8 Stirred and Rotating Drum Bioreactor -- 13.4 Conclusion -- Acknowledgment -- References -- Chapter 14 Microbial Cell Factories for Nitrilase Productionand Its Applications -- 14.1 Introduction -- 14.2 Nitrilase Categorization, Sources, Metabolism, and Production Process -- 14.2.1 Nitrilase Categorization -- 14.2.2 Nitrilase Sources -- 14.2.3 Nitrilase in the Metabolism of Nitriles -- 14.2.4 Isolation and Screening of Nitrilase-Producing Microorganisms.; 14.2.5 Cultivation of Nitrilase-Producing Microbes -- 14.2.6 Nitrilase Production in Bioreactor -- 14.3 Nitrilase in the Biotransformation of Nitriles -- 14.3.1 Aliphatic Acids -- 14.3.2 Aromatic Acids -- 14.3.3 Arylacetic Acids -- 14.4 Conclusion -- References -- Chapter 15 Chemistry and Sources of Lactase Enzyme with an Emphasis on Microbial Biotransformation in Milk -- 15.1 Introduction -- 15.2 Lactase Enzyme -- 15.3 Sources of Lactase -- 15.3.1 Plants -- 15.3.2 Bacteria -- 15.3.3 Yeasts -- 15.3.4 Molds -- 15.4 Microbial Biotransformation of Lactase Enzyme -- 15.4.1 Improvement of Microbial Strains -- 15.4.2 Galactooligosaccharide Synthesis and Transglycosylation -- 15.4.3 Lactose Intolerance -- 15.5 Conclusion -- References -- Chapter 16 Microbial Biogas Production: Challenges and Opportunities -- 16.1 Introduction -- 16.2 Generalities of Biogas Production: the Process and Its Yields -- 16.3 Feedstocks Used in Biogas Production and Their Characteristics -- 16.4 Microbial Biodiversity in Biogas Production -- 16.4.1 Generalities -- 16.4.2 Anaerobic Fungi in Biogas Production -- 16.4.3 Anaerobic Bacteria in Biogas Production -- 16.4.4 Methanogenic Archaeal and Algae in Biogas Production -- 16.5 The Role of the Enzymes in Biogas Production -- 16.6 Challenges and Opportunities in Biogas Production -- 16.6.1 Challenges for Biogas Production -- 16.6.2 Opportunities for Biogas Production -- References -- Chapter 17 Molecular Farming and Anticancer Vaccine: Current Opportunities and Openings -- 17.1 Introduction -- 17.2 Vaccines and the Possibility in Noncommunicable Diseases -- 17.3 Vaccine Production -- 17.3.1 Cancer Vaccine -- 17.4 Types of Cancer Vaccine -- 17.5 Microbial Production of Anticancer Vaccine: Challenges and Opportunities -- 17.5.1 Yeast-Based Cancer ; Vaccine (YBCV) -- 17.5.2 Bacteria-Based Cancer Vaccine (BBCV) -- 17.6 Conclusion.; References.