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Record Nr. |
UNINA9910830283903321 |
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Titolo |
Medical biostatistics for complex diseases [[electronic resource] /] / edited by Frank Emmert-Streib and Matthias Dehmer |
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Pubbl/distr/stampa |
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Weimheim, : Wiley-VCH, 2010 |
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ISBN |
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1-282-68778-6 |
9786612687785 |
3-527-63033-3 |
3-527-63034-1 |
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Descrizione fisica |
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1 online resource (413 p.) |
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Altri autori (Persone) |
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Emmert-StreibFrank |
DehmerMatthias |
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Disciplina |
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Soggetti |
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Medicine - Research - Statistical methods |
Medical statistics |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Medical Biostatistics for Complex Diseases; Foreword; Contents; Preface; List of Contributors; Part One: General Biological and Statistical Basics; 1 The Biology of MYC in Health and Disease: A High Altitude View; 1.1 Introduction; 1.2 MYC and Normal Physiology; 1.3 Regulation of Transcription and Gene Expression; 1.4 Metabolism; 1.5 Cell-Cycle Regulation and Differentiation; 1.6 Protein Synthesis; 1.7 Cell Adhesion; 1.8 Apoptosis; 1.9 MicroRNAs; 1.10 Physiological Effects of Loss and Gain of c-myc Function in Mice; 1.10.1 Loss of Function |
1.10.2 Gain of Function: Inducible Transgenic Animals1.11 Contributions of MYC to Tumor Biology; 1.12 Introduction of Hematopoietic Malignancies; 1.13 Mechanisms of MYC Dysregulation in Hematological Malignancies; 1.14 Mutation(s) in the MYC Gene in Hematological Cancers; 1.15 Role of MYC in Cell Cycle Regulation and Differentiation in Hematological Cancers; 1.16 Role of BCR Signaling in Conjunction with MYC Overexpression in Lymphoid Malignancies; 1.17 Deregulation of Auxiliary Proteins in Addition to MYC in Hematological Cancers; 1.18 Conclusion; References |
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