Philo : in ten volumes (and two supplementary volumes)

• Record Nr.: UNIBAS000013037
• Autore: Philo Alexandrinus <20 a.C.-ca. 45>
• Pubbl/distr/stampa: Cambridge, Massachusetts : Harvard University Press; London : <<William>> Heinemann
• ISBN: 0-674-99249-0; 0-434-99226-7; 0-674-99250-4; 0-434-99227-5; 0-674-99287-3; 0-434-99261-5; 0-674-99319-5; 0-434-99289-5; 0-674-99353-5; 0-434-99320-4; 0-674-99417-5; 0-434-99379-4; 0-674-99418-3; 0-434-99380-8; 0-674-99442-6; 0-434-99401-4
• Descrizione fisica: 12 volumi ; 17 cm
• Collana: The Loeb classical library
• Disciplina: 220.609015
• Lingua di pubblicazione: Inglese; Greco antico
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Traduzione inglese con testo greco a fronte
• Nota di contenuto: Vol. I: De opificio mundi ; Legum allegoria / with an English translation by F. H. Colson and the Rev. G. H. Whitaker. - 1981. - XXXVI, 483 p. Vol. II: De Cherubim ; De sacrificiis Abelis et Caini ; Quod deterius potiori insidiari soleat ; De posteritate Caini ; De gigantibus / with an English translation by F. H. Colson and the Rev. G. H. Whitaker. - 1979. ; - VIII, 503 p. Vol. III: Quod Deus sit immutabilis ; De agricultura ; De plantatione ; De ebrietate ; De sobrietate / with an English translation by F. H. Colson and the Rev. G. H. Whitaker. - 1968. - X, 511 p. Vol. IV: De confusione linguarum ; De migratione Abrahami ; Quis rerum divinarum heres ; De congressu eruditionis gratia / with an English translation by F. H. Colson and the Rev. G. H. Whitaker. - 1985. - XII, 581 p. Vol. V: De fuga et inventione ; De mutatione nominum ; De somniis / with an English translation by F. H. Colson and the Rev. G. H. Whitaker. - 1968. - X, 625 p. Vol. VI; De Abrahamo ; De Josepho ; De vita Mosis / with an English translation by F. H. Colson. - 1984. - XX, 611 p. Vol. VII; De decalogo ; De specialibus legibus I-III / with an English translation by F. H. Colson. - 1984. - XX, 640 p. Vol. VIII: De specialibus legibus IV ; De virtutibus ; De praemiis et poenis / with an English translation by F. H. Colson. - 1968. - XXVI, 456 p. Vol. IX: Quod omnis probus liber sit ; De vita contemplativa ; In Flaccum ; Hypothetica ; De providentia / with an English translation by F. H. Colson. - 1967. - XII, 546 p. Vol. X: Embassy to Gaius / with an English translation by F. H. Colson ; Indices / J. W. Earp. - 1971. - XXXVIII, 519 p. Suppl. I: Questions and answers on Genesis / translated from the ancient armenian version of the original greek by Ralph Marcus. - 1979. - XX, 551 p. Suppl. II: Questions and answers on Exodus / translated from the ancient armenian version of the original greek by Ralph Marcus. - 1970. -VIII, 306 p.

Protein Degradation [[electronic resource] ] : Cell Biology of the Ubiquitin-Proteasome System

• Record Nr.: UNINA9910830200703321
• Autore: Mayer R. John
• Pubbl/distr/stampa: Hoboken, : Wiley, 2008
• ISBN: 1-282-37219-X; 9786612372193; 3-527-62022-2; 3-527-62029-X
• Descrizione fisica: 1 online resource (254 p.)
• Collana: Protein Degradation ; ; v.7
• Altri autori (Persone): CiechanoverAaron J; RechsteinerMartin
• Disciplina: 572.76; 612.3/98
• Soggetti: Cell Physiology; Proteins - Metabolism; Proteins - metabolism; Proteins --Metabolism; Ubiquitin; Ubiquitin - physiology; Animal Biochemistry; Human Anatomy & Physiology; Health & Biological Sciences
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di contenuto: Protein Degradation; Contents; Preface; List of Contributors; 1 Ubiquitin: A New Player in the Peroxisome Field; 1.1 Introduction; 1.2 Matrix Protein Import into Peroxisomes is Mediated by Cycling Receptors; 1.3 Pex5p is Monoubiquitinated in Wild-type Cells, but Polyubiquitinated in Late-acting pex Mutants; 1.4 Ubiquitination of Pex18p; 1.5 Role for the RING Finger and AAA Peroxins in Pex5p Ubiquitination and Recycling; 1.6 Pex5p Monoubiquitination: A Role in Receptor Recycling; 1.7 Conclusions/Future Prospects; Acknowledgements; References; 2 The Ubiquitin Proteasome System and Muscle Development2.1 Introduction; 2.2 Muscle Histology; 2.3 UPS and Developing Muscle; 2.3.1 Ubiquitin-dependent Degradation of MyoD; 2.3.2 Degradation of MyoD by SCF(MAFbx); 2.3.3 Other Muscle Regulatory Factors; 2.4 UPS and Organizing Muscle; 2.4.1 Ozz-E3-dependent β-Catenin Regulation in the Muscle; 2.4.2 Regulation of Myosin Assembly by CHN-1 and UFD-2; 2.5 UPS and Muscle Destruction or Degeneration; 2.5.1 N-end Rule and Muscle Atrophy; 2.5.2 MuRFs, E3 Enzymes in Atrophying Muscles; 2.5.3 Atrogin-1/MAFbx Function in Muscle Atrophy; 2.5.4 Activation of Muscle-atrophy Pathways2.6 Concluding Remarks; References; 3 The COP9 Signalosome: Structural and Biochemical Conservation and Its Roles in the Regulation of Plant Development; 3.1 Introduction; 3.2 The Plant COP9 Signalosome; 3.3 CSN Involvement in the Ubiquitin-Proteasome Pathway; 3.4 Plant CSN Biochemical Activities; 3.4.1 Deneddylation; 3.4.2 Subcellular Partitioning; 3.5 CSN Functions in Plant Development; 3.5.1 Floral Development; 3.5.2 Responses to Plant Hormones; 3.5.3 Disease Resistance; 3.5.4 Photomorphogenesis; 3.6 Conclusions; References; 4 Ubiquitin and Protein Sorting to the Lysosome4.1 Introduction; 4.2 Identification of Ubiquitin as an Endosomal Sorting Signal; 4.3 Ubiquitin-mediated Sorting at the Endosome: The MVB Sorting Machinery; 4.3.1 Endosome-associated Ubiquitin Interacting Domains: Structure and Function; 4.3.2 The Hrs-STAM Complex and the Endosomal Clathrin Coat; 4.3.3 GGA and Tom1: Alternative Sorting Adapters?; 4.3.4 The ESCRT Machinery; 4.3.5 Vps4-SKD1; 4.4 Ubiquitin Ligases and Endosomal Sorting; 4.4.1 Nedd4 Family; 4.4.2 c-Cbl; 4.5 Endosomal DUBs; 4.5.1 Ubp1 and Ubp2; 4.5.2 Doa4; 4.5.3 UBPY; 4.5.4 AMSH; 4.6 Polyubiquitin Linkages and Endocytosis4.6.1 Proteasome Involvement in Endocytic Sorting; 4.6.2 K63-linked Ubiquitin; 4.7 Future Directions; Acknowledgements; References; 5 ISG15-dependent Regulation; 5.1 Introduction and Overview; 5.2 The Discovery of ISG15; 5.3 Structure and Properties of the ISG15 Protein; 5.4 The ISG15 Conjugation Pathway; 5.4.1 Activation of ISG15 by UbE1L; 5.4.2 UbcH8 is an ISG15-specific Conjugating Enzyme; 5.4.3 Candidate ISG15-specific Ligases; 5.5 Regulation of Intracellular ISG15 Pools; 5.6 Functional Roles for ISG15; 5.6.1 ISG15 as an Extracellular Cytokine; 5.6.2 Role of ISG15 in the Antiviral Response
• Sommario/riassunto: The third of four volumes discusses the role of ubiquitin-mediated protein breakdown in cellular regulation and physiology. Required reading for molecular biologists, cell biologists and physiologists with an interest in the topic.