Natural Products and Their Bioactives in Antidiabetic Drug Discovery

• Record Nr.: UNINA9910830035903321
• Autore: Pandey Kanti Bhooshan
• Pubbl/distr/stampa: Newark : , : John Wiley & Sons, Incorporated, , 2023; ©2024
• ISBN: 1-119-98334-7; 1-119-98332-0
• Descrizione fisica: 1 online resource (352 pages)
• Altri autori (Persone): SuttajitMaitree; AtukerenPinar
• Disciplina: 616.4/6206
• Soggetti: Hypoglycemic agents - Development; Bioactive compounds; Diabetes - Research
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Nota di contenuto: Intro -- Natural Products and their Bioactives in Antidiabetic Drug Discovery -- Contents -- List of Contributors -- Preface -- Part I Fundamental Concepts of Diabetes Mellitus and Drug Discovery Process -- 1 Diabetes Mellitus and Natural Product-based Drug Discovery: Novel Directions -- 2 Marine Natural Products in the Management of Diabetes Mellitus -- 3 Carbohydrate-based Antidiabetic Agents from Natural Products -- 4 Functional Foods in Clinical Trials in the Intervention of Diabetes Complications -- 5 Role of Nanotechnology in Refining the Antidiabetic Activities of Plant Derived Bioactives -- Part II Bioactive Compounds Against Type 1 Diabetes Mellitus -- 6 Epidemiology and Genetics of Type 1 Diabetes Mellitus: The Effect of the Mediterranean Diet -- 7 The Emerging Role of Plant Polyphenols in the Management of Type 1 Diabetes Mellitus -- 8 Bioactives as Modulators of β-cells and Immunity in Therapy of Type 1 Diabetes Mellitus -- 9 Obesity in Type 1 Diabetes Mellitus: Clinical Impact and Nutritional Therapy -- 10 Protective Effects of Natural Non-insulin Drugs against Type 1 Diabetes Mellitus -- Part III Bioactive Compounds Against Type 2 Diabetes Mellitus -- 11 Age-induced Biomarkers of Oxidative Stress in Type 2 Diabetes Mellitus: Role of Plant Polyphenols ; -- 12 Bioactives from Clove Oil for Antibacterial Wound Dressings for the Treatment and Management of Wounds in Type 2 Diabetes Mellitus -- 13 Nutritional Features and Bioactivities of Thymoquinone against Type 2 Diabetes Mellitus -- 14 Effect of Resveratrol and Catechins in Maintaining Redox Homeostasis during Type 2 Diabetes Mellitus -- 15 Cannabis: Action Mechanisms and Potential Roles in the Management of Type 2 Diabetes Mellitus -- Part IV Gestational Diabetes: Prevention and Management by Natural Compounds.; 16 Epidemiology of Gestational Diabetes Mellitus: Preventive Significance of Dietary Pattern -- 17 Biomarkers of Gestational Diabetes Mellitus, Dietary Polyphenols, and Drug Discovery -- 18 Medicinal and Aromatic Plants in the Prevention of Gestational Diabetes and Associated Consequences: Current Insights -- 19 Enhancement of Insulin Sensitivity and Management of Lipid Disorders during Gestational Diabetes Mellitus: Role of Capsaicin -- 20 Effects of Natural Products on the Genetics of Gestational Diabetes Mellitus -- Index -- EULA.
• Sommario/riassunto: "Diabetes mellitus DM which is commonly known as sugar disease has now become bitter for health and this metabolic disease is increasing worldwide at an alarming rate. The combination of chronic pathological disorders in pancreatic leading to persistent hyperglycemia is connected to serious organ damage followed by failure including kidneys eyes feet nerves brain gastrointestinal tract and cardiovascular system in DM."--