1.

Record Nr.

UNINA9910829855803321

Autore

Dörwald Florencio Zaragoza

Titolo

Side reactions in organic synthesis : a guide to successful synthesis design / / Florencio Zaragoza Dörwald

Pubbl/distr/stampa

Weinheim : , : WILEY-VCH Verlag, , 2005

ISBN

1-280-52013-2

9786610520138

3-527-60426-X

3-527-60498-7

Descrizione fisica

1 online resource (392 p.)

Disciplina

547.2

Soggetti

Organic compounds - Synthesis

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Organic synthesis : general remarks. -- Stereoelectronic effects and reactivity. -- The stability of organic compounds. -- Aliphatic nucleophilic substitutions : problematic electrophiles. -- The alkylation of carbanions. -- The alkylation of heteroatoms. -- The acylation of heteroatoms. -- Palladium-catalyzed C-C bond formation. -- Cyclizations. -- Monofunctionalization of symmetric difunctional substrates.

Sommario/riassunto

Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds.This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A mu