1.

Record Nr.

UNINA9910829168903321

Titolo

Immunopotentiation

Pubbl/distr/stampa

Amsterdam, : Elsevier, 1973

ISBN

9786613693754

9781280783364

1280783362

9780470720011

0470720018

9780470717684

0470717688

Edizione

[1st ed.]

Descrizione fisica

1 online resource (368 pages)

Collana

Ciba Foundation symposium (new series) ; ; 18

Disciplina

574.2/9

Soggetti

Immunological adjuvants

Tumors - Immunological aspects

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Symposium on Immunopotentiation, held at the Ciba Foundation, London, 18th-19th January 1973"--Participants page.

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

Immunopotentiation; Contents; Introduction; The cellular targets for the action of adjuvants : T-adjuvants and B-adjuvants; Discussion; The relation of lymphocyte trapping to the mode of action of adjuvants; Discussion; Immunopotentiation by mycobacteria in complete Freund-type adjuvant as the failure of normal immunological homeostasis; Discussion; Effects of adjuvants on different cell types and their interactions in immune responses; Discussion; Cellular mechanisms underlying the adjuvant activity of Corynebacterium parvurn: interactions of activated macrophages with T and B lymphocytes

DiscussionChemotaxis of macrophages : the role of a macrophage-specific cytotaxin from anaerobic corynebacteria and its relation to immunopotentiation in vivo; Discussion; The allogeneic effect on the immune system and its potential applications to tumour immunity; Discussion; Mitogens as probes for immunocyte activ- ation : specific and non-specific paralysis of B cell mitogenesis; Discussion; General Discussion I The T cell-deprived mouse; The use of viruses as



immunological potentiators; Discussion

Corynebacterium parvum, a potent immunostimu-lant in experimental infections and in malignanciesDiscussion; Orchidectomy as a method of immunopotentiation in mice; Discussion; The nature of immunopotentiation by the anti-tumour polysaccharide lentinan and the significance of biogenic amines in its action; Discussion; The effect of Corynebacterium parvum and other reticuloendothelial stimulants on transplanted tumours in mice; Discussion; Attempt at using systemic immunity adjuvants in experimental and human cancer therapy; Discussion

General Discussion II Restoration of immune capability in cancer patientsSites of action of adjuvants; Conclusion; Index of contributors; Subject index

Sommario/riassunto

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.