1.

Record Nr.

UNINA9910828484403321

Autore

Tollefsbol Trygve O.

Titolo

Personalized epigenetics / / Trygve O. Tollefsbol ; designer, Mark Rogers ; contributors, Vanessa Aguiar-Pulido [and forty five others]

Pubbl/distr/stampa

Amsterdam, Netherlands : , : Academic Press, , 2015

©2015

Descrizione fisica

1 online resource (611 p.)

Collana

Translational Epigenetics Series

Disciplina

572.865

Soggetti

Epigenetics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

6. BRAIN CELLULAR HETEROGENEITY AND METHYLATION VARIATION

Sommario/riassunto

Personalized Epigenetics discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy.    The book details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, and noncoding RNA, and the diagnostic, prognostic, and therapeutic potential of the field, it also reviews the impact of the environment on epigenetic variations among individuals and the role of pharmacology and drug de